Update: 2018 Summary on L Reuteri.
Lactobacillus Reuteri is near the top of my list of probiotics. The reason is simple, in almost all mammals it is the species that is usually most seen in healthy individuals. Often studies reported something like 55% of the Lactobacillus species are Reuteri. It is NOT in most probiotics. L.Reuteri is by far the Lactobacillus that is most likely to persist in the gut, most Lactobacillus are literally flow-thru, they have an impact, (in fact, one antibiotic (not used much today) is extracted from Lactobacillus Acidopholus), but do not establish a colony. It produces reuterin and cobalamin (B12), which no other Lactobacillus does.
My own practice is to buy as many different strains of L.Reuteri that I can find. For maintenance, I do a week of it every 2-3 months. It should be taken before meals and with some fat, see this post for details.
For a more technical description of L.Reuteri, see
Glutathione is one of L.Reuteri essential foods (http://www.ncbi.nlm.nih.gov/pubmed/21585317 ) so make sure that you supplement with it (I would suggest taking that 1 hr before the L.Reuteri) . This feeding of L. Reuteri may be one reason that it has positive effects on CFS patients (although the why of taking it comes from a different model).
- [Effect of acupuncture on serum malonaldehyde content, superoxide dismutase and glutathione peroxidase activity in chronic fatigue syndrome rats].
- Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathioneand clinical symptoms implicate oxidative stress in disorder pathophysiology.
- Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway that may be associated with coronary artery disease and neuroprogression in depression.
- Competition for glutathione precursors between the immune system and the skeletal muscle: pathogenesis of chronic fatigue syndrome.
The reason that some people may be non-responders to Gluthathione could be as simple as having no L.Reuteri left to feed!
Bottom line: L Reuteri and Glutathione should be taken together – taking one without the other may result in little or no effect.
- Gluthathione (and No, I don’t know which is better: no studies)
- L.Reuteri containing probiotics