Below is a simple picture of the model that I use in understanding CFS. This model also leads me into certain direction for items to investigate. The very short general model is this:

  • An event (infection, stress, etc) resulted in a stomach upset — the bacteria shifts in response
  • The event ends
    • 95% of people stomach returns to prior state quickly. The reminder take longer
    • Some do not return (CFS/IBS/FM) and the new bacteria mixture produces a different mixture of metabolites (chemicals)
    • These metabolites produce the symptoms including under absorption and over-production.


Some event (roots) changed the microbiome (thunk) which results and depends on a variety of factors