The Prescript-Assist Broad Spectrum Probiotic Prebiotic Complex is very unusual, and appear very applicable to IBS, CFS, FM patients. It is described at this UK site as well as at (but not It contains none of the usual bacterias!


The original formula has changed by 50%, the studies cited do no apply to the new product. For more information see this update


  • Pseudomonadales
    • Arthrobacter agilis,
    • Arthrobacter citreus,
    • Arthrobacter globiformis,
    • Arthrobacter luteus,
    • Arthrobacter simplex,
    • Acinetobacter calcoaceticus,
    • Azotobacter chroococcum,
    • Azotobacter paspali,
    • Pseudomonas dentrificans,
    • Pseudomonas flourescens,
    • Pseudomonas glathei,
  • Rhodospirillales
    • Azospirillum brasiliense,
    • Azospirillum lipoferum,
  • Firmicutes
    • Bacillus brevis,
    • Bacillus marcerans,
    • Bacillus pumilis,
    • Bacillus polymyxa,
    • Bacillus subtilis,
    • Bacteroides lipolyticum,
  • Bacteroidetes
    • Bacteriodes succinogenes,
  • Micrococcineae
    • Brevibacterium lipolyticum,
    • Brevibacterium stationis,
  • Coryneform
    • Kurtha zopfil,
  • Clostridiales Family XI Incertae Sedis
    • Myrothecium verrucaria,
  • Polyporales
    • Phanerochaete chrysosporium,
  • Streptomyces fradiae,
  • Streptomyces celluslosae,
  • Streptomyces griseoflavus

In terms of PubMed Studies, there are two, both done by Battelle Seattle Research Center, Washington, USA.

Both studies dealt with Irritable Bowel Syndrome which is often co-morbid with CFS. From these studies:

  •  At >or=52-week follow-up, the rate of remissions was 81.5% to 100% (P < 0.003).
  • This study identified 3 subsyndromic factors of IBS: general ill feelings/nausea, indigestion/flatulence, and colitis. In this methodologically oriented double-blind study in patients with IBS, combined probiotic-prebiotic treatment with Prescript-Assist was associated with significant reductions in these factors.

There have been no studies with CFS or FM. Studies with Lactic acid bacteria and IBS found “The probiotic combination was not significantly superior to the placebo in relieving symptoms of IBS.”.

Bottom line: NO LONGER a definite thumbs up on trying this for at least 4 weeks.