Ashwagandha is an ideal supplement for CFS. It improves depression, and improves handling of stress. Stress is a contributing factor for onset and is associated with as a trigger for flares. This should reduce the number of flares and shorten their duration.
In terms of inflammation cytokines,
- Increases IL-2, IFN Gamma
- Reduces TNF-alpha
In terms of thick blood, it increases coagulation time(good) and the effect continues for up to 7 days after taking.
Lastly, it protects the mind, a neuroprotective and anti-oxidant. SPECT scans shows inflammation in the brain of 70+% of CFS patients, this should reduce it and protect the brain (hopefully reduce the 1% loss/year of some brain matter seen in studies).