What does going through multiple families of antibiotics do to gut bacteria?  Kill many of them. Many people will not take antibiotics because they kill gut bacteria — not all gut bacteria, just some species. Jadin’s regime of rotating antibiotics is a perfect way of disrupting this stable bacteria alteration.

This page is based on studies not done on humans with cfs. Readers of this site has shared their experience on a survey. The survey may help guide you to the best decisions/ best odds.

  • I constructed the table below ‘unscientifically’ by just googling the antibiotic family and the bacteria family and seeing what the usual result was. The impact of the families of antibiotic appears  to be a good match for what we want to have happen. Jadin’s protocol was based on experimentation on people with the appearance of occult illness due to Rickettsia. They did not have the labs we have. They found traces of Rickettsia in the tissue and went down a logical path that said “Oh we have a resistant version — we need to try other antibiotics!” This was exactly the logic that my MD used for my first onset of CFS (before it was a known condition).
Antibiotic Family Klebsiella/Enterobacter Enterococcus Streptococcus E.Coli Bifidobacterium Lactobacillus Score for CFS
In CFS Patients HIGH HIGH HIGH low low low *
Tetracyclines Effective Resistant Resistant Resistant Resistant Resistant 1
Macrolides Effective Resistant Resistant Resistant Resistant Resistant 1
Quinolone Resistant Effective Resistant Resistant Resistant Effective -1
Metronidazole Effective Resistant Resistant Effective Resistant Resistant -1
Rifampicin Resistant Resistant* Resistant * Resistamt Effective
  • * Was Effective once, but significant resistant has developed
  • ++ Some species are resistant, but many are not

Other Antibiotics (by request). Score done by 1 for each EFFECTIVE in high (good) and -2 for each EFFECTIVE in low (I view the harm is more significant than the good)

Antibiotic Family Klebsiella/Enterobacter Enterococcus Streptococcus E.Coli Bifidobacterium Lactobacillus Score for CFS
In CFS Patients HIGH HIGH HIGH low low low *
Amoxycillin Resistant [*] Effective[*] Effective Resistant Effective[*] Effective[*] -2
Silver Resistant Effective Effective Resistant Effective Effective -2
Lactobacillus probiotics (General) Resistant [2014] Resistant [2014] Effective Effective Effective -3

What is seen is that the probable over growths are reduced with this protocol as reported in the 1998 Conference Presentation, and most of the under growths are not impacted. Similar results were reported for two species: “The viable count of D-lactic acid producing Enterococcus and Streptococcus spp. in the faecal samples from the CFS group.. were significantly higher than those for the control group ” Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome. [2009]  High-throughput 16S rRNA gene sequencing reveals alterations of intestinal microbiota in myalgic encephalomyelitis/chronic fatigue syndrome patients [2013]


Jadin and Occult Infections

Cecile Jadin, M.D., has had great success with an antibiotic rotation that the Pasteur Institute had used 70 years ago to deal with what they felt were occult infections[Presentation].  In reflection, I can very well see how they came to that conclusion.  If the symptoms of an infection that was successfully treated returned but cannot be detected then a reasonable assumption was that it was somehow “occult” or hidden. Today it is commonly called “Post-Infection Syndrome”.  If you shift your perspective to the symptoms not being caused directly by the infection but by the alteration in the gut bacteria that the infection caused then it is not the infection returning in a hidden form — it is the gut bacteria alteration becoming stable in the “disease pattern”. Without modern research testing facilities, it is impossible to differentiate them.