A second BioScreen Report

I had done a BioScreen report on an earlier post. The details of the microbiome is a lot less than uBiome, but in some way better for specific items — namely, bacteria treatable by antibiotics.

This person has used Proton-pump inhibitors in the past (see below)

Standard Checks

  • No Lactobacillus
  • No Bifidobacteria
  • High E.Coli — The same as the prior post — this may be a test methodology issue

Compare to other report

  • This person is also high in Streptococcus (50x or more than reference) but with different strains (and one in common)
  • No Yeast here
  • This person has high Klebsiella pneumoniae (which was reported in the 1998 study as being seen)

bio3

bio1

bio2

Analysis

With the high E.Coli and Strepoccocus, it was interesting to find that some species can co-exist together:

Using DataPunk, we can go to the species level (finer than the genus level of uBiome). Unfortunately this does not buy us any more information for these than the genus would.

  1. Streptococcus parasanguinis (species) 
  2. Streptococcus salivarius (species) 
  3. Streptococcus anginosus group (species group) 
  4. Klebsiella pneumoniae (species) 
  5. Erysipelato- clostridium ramosum (species) 

NUTRIENTS/ SUBSTRATES

INHIBITED BY

ENHANCED BY

INHIBITS

 

Antibiotics

Bottom Line

A low or no glucose diet may be beneficial (see this post for information) to starve the bacteria. This is not a low or no sugar diet, this is for a specific type of sugar. Also, you may wish to review the suggestions on my earlier  post.

  • With antibiotics, rotation is clearly the preferred approach because of the high resistance rates reported.  The three antibiotics: cefuroxime, minocycline and a penicillins seem reasonable.
  • The non-antibiotic route are likely the items listed under inhibit, plus Rosehip and  pomegranate blossom teas.

Which test is better – Bioscreen or uBiome? If you have a physician that is willing prescribe antibiotics, then Bioscreen is better because you are able to better determine the candidate antibiotics. Unfortunately, you will not see overgrowth of other bacteria genus.

If you are in a “diet, herb, supplements only” path — then uBiome is better. One of the difficulties with uBiome results is that for many of the bacteria genus we do not know which antibiotics are resistant. In many cases, we do know something that inhibits them.

As always, consult with your knowledgeable medical professionals before making any changes.

 

 

 

 

 

 

A very atypical uBiome

A person who have done their uBiome several times over the last few years was kind enough to share their results. The numbers blew me away!!! If I had gotten a single lab with these numbers, I would suspect a lab error… but clearly that is not the case.

Standard Criteria

  • Lactobacillus is typical very low
  • Bifidobacteria is not — BUT if you look at the overgrowth, it is 1/100 (1%) compare to some overgrowth,,,
  • Low or no E.Coli
    • Not directly reported, but it parent is: Enterobacteriaceae  which is 12% of the reference group
  • High Akkermansia (parent is Verrucomicrobiaceae) 525% – 6500% of the reference group

Patient History

  • Onset was in 2009 while living in a moldy apartment
    • Trigger may have been wither H1N1 Flu or stomach bug overseas
    • POTS, brain fog, PEM, Sinus, histamine issues
  • Hypersensitive to mold
  • Reacts mildly to fragrances
  • No longer living in a mold environment

2013 uBiome

  • Bifido: 2.27
  • Lacto: 0.02
9/13/15 6/23/16 10/18/2016 6/13/2017
15 16 1016 17
  • Bifido: 0.27
  • Lacto: 0.07
  • Bifido: 1.23
  • Lacto: 0.0
  • Bifido: 1.45
  • Lacto: 0.06
  • Bifido: 0.71
  • Lacto: <0.01
This is using the latest results (6/13/2017). The number indicates the order in the results above. The data is from DataPunk.net

NUTRIENTS/ SUBSTRATES

INHIBITED BY

ENHANCED BY

NOTE: the comparison for Bifido and Lacto were against different references above.

Analysis

The above is a challenge. Please note that Lactibacillus  (Genus) includes both Lactobacillus and Bifidobacteria. So the high number above is due to bifidobacteria.

I have worked only the current state — and included the known nutrients for these bacteria. My initial inclination is to starve them of the nutrients they need.  D-Glucose which is blood sugar. This means going to NutritionData.Self.com listing high glucose foods and avoiding them. Some possible surprises for food to avoid:

  • Apricots, Pineapples, Dates, Honey, Pomegranate juice, Grape juice… i.e. most fruits
  • Pop, Melons, Squash, dill pickles, Cabbage, tomato products, radishes etc.

The person may wish to work with a nutritionist (if they can get their head around working on a low glucose diet — which is different from a low sugar diet. glucose is a specific type of sugar).

As shown above — walnuts, Saccharomyces boulardii and Proton-pump inhibitors (PPI) – are clearly to be avoided. While Flaxseed is on both inhibits and enhanced, it appears that it will inhibits a lot more than it enhances, and should be part of the daily diet. Flaxseed porridge with brown sugar for breakfast? (Brown sugar is sucrose, not glucose)

Bottom Line

The problem with many bacteria genus overgrowth is when to stop searching for a magical super set of supplements and food changes. My suggestion here is not to go on a low sugar diet (which will impact all bacteria), but a low glucose diet because the two biggest over growths feeds on this. This is some ways may be contrary to common sense health advice such as eating lots of fruits. You may wish to read wikipedia on glucose syrup (something to avoid)

As always consult with a knowledgeable medical professional (which may include a nutritionist) before any changes of supplements or diet. Keyword is knowledgeable

Addendum

Q: You say sugar is sucrose and not glucose, but isn’t sucrose broken down into 50/50 glucose and fructose?
CFS Remission Correct — since we are talking about gut bacteria… the glucose would be delayed and more important — the bacteria favoring sucrose and fructose would be increased. Glucose based bacteria will be dependent on other bacteria processing first, not the direct food intake.