Guest Post: ME/CFS, the Sphinx, and the Microbiome

Estácio Ferreira Ramos M.D. CEO, Cytomica®, Inc. | CTO, Microbio.World® | Hematology-

There is a giant sphinx of evidence showing that restricted access to the planet’s microbiome is the fundamental etiogenic factor of ME/CFS, but most scientists refuse to face this veritable monument of information.

Let us see a few things.

There are 63 recognized epidemics of the disease, 31 of which occurred in hospitals, just affecting health professionals. The first, in 1934, hit all 198 nurses and doctors at the Los Angeles County Hospital, but curiously, none of the patients admitted to the institution. Until today, the predilection of the disease for health professionals is an undisputed fact; why is that? …

The fact is, health professionals spend most of their lives in aseptic environments, where access to the natural microbiome is blocked. Mechanical barriers (masks, gloves, caps, sterile clothing, disposable aprons, safety glasses, shoe covers), chemicals (frequent washing of hands with detergents, abusive and continuous use of degerming agents (alcohol, chlorhexidine, iodine, hypochlorite, etc.), and even cultural behaviors block the access to beneficial microorganisms. In 2010, I saw in London the recommendation to avoid kisses on the cheeks and handshakes on hospital premises.

England is one of the nations with the highest incidence of ME/CFS, and in which a culture of greater distance and respect for personal space prevails. With the COVID-19 pandemic, this culture has been intensified throughout the world, a fact that made me foresee the global increase of ME/CFS, and change the title of my work, from Outbreak 64© to Pandemics Entangled©.

Taking the first epidemic of ME/CFS as a paradigm, in 1934 Pasteur had already demonstrated the bacterial origin of the infections, but penicillin was still not available, and the hospital had many infections; hygiene norms were therefore neurotic. In addition, foods were also strictly sterile, and there was a boom in spam and canned foods, considered safer because they were sterile (the occurrence of botulism in the first canned foods led the industry to intensify food sterilization systems in cans).

DeMeirleir et.al. advocate that the ingestion of metals by people living with dysbiosis triggers or aggravates ME/CFS, and the welds of the first cans contaminated the food they contained with toxic metals.

The other epidemics victimized human groups in relatively isolated or restricted coexistence: convents, military bases, schools, a ship, industries, groups of athletes, having in common few interpersonal contacts, and cafeterias with carefully sterile food, aiming at the prevention of food infections. I believe that cold winters also favor the emergence of disease, by limiting the expansion of the natural microbiome.

Read under this light, the long history of ME/CFS and fibromyalgia, thoughtfully summarized in Chapter 9 of Pandemics Entangled©, makes this truth much easier to understand and accept.

Besides, considering the Epidemiology of ME/CFS, summarized in Chapter 15, it solidifies the understanding that the greater symbiosis breakdown leads to this confusing spectrum of diseases.

Adding to this set of evidence is the fact that isolated cases of these diseases began to affect middle-aged upper-middle-class women: more acculturated mothers and grandmothers, with access to better sanitation, and higher hygienic standards; determined to make food safer (meaning sterile) for their children and grandchildren.

I am not refuting here any of the hundreds, perhaps thousands, of research that demonstrates countless pathophysiological mechanisms involved in ME/CFS (although many are refutable); I just focus on the essential condition that leads to the development of the disease: the war imposed by civilization on the microbiome of the blue planet.

I am sure that in the near future a good epidemiologist with access to the internet, and with some software or calculator, will confirm my theory; which supports and has been strengthened by the research I have carried out over fifteen years.

In addition, I envision the moment when artificial intelligence resources and/or a broader meta-analysis will seal this knowledge.

This sphinx will not devour me. Neither will those willing to accept the intuitive knowledge that deciphers it.

The worst blind is the one who refuses to see.

Source: https://www.linkedin.com/pulse/mecfs-sphinx-microbiome-est%C3%A1cio-ferreira-ramos-m-d-/