Licorice – Glycyrrhiza


When I came down with CFS about 1999, Licorice was one of the items that assisted me to full remission by 2001.

Licorice comes in several forms, we are NOT talking about a confectionery candy. There is a pure Licorice candy called Spezzata which Cap’n Dave introduced me to in 1999 and which I continues to use. The active ingredient is Glycyrrhiza.

What does it do?

It does almost everything that you really want from a supplement: PubMed studies report that it alters microfloras, is anti-bacterial, Inhibits viruses(including EBV via a unique mechanism, and rota-virus). It reduces inflammation, depression and crosses the blood-brain-barrier.

In terms of the thyroid, it increases the biological half-life of cortisol and potentiates the action of hydrocortisone.

It has been documented in patient studies to reduce symptoms — in fact, there are published reports of remission. This report is very creditable if EBV is the primary pathogen.

Three ways of taking

The report of remission was by dissolving taking 2.5 grams of extract dissolved in a pint of milk. Taking 40 grams/day as capsules did not result in remission.

The last  approach is using Spezzata and dissolving it in the mouth (possibly with warm milk, hot chocolate or a latte). This is my usual method.

Licorice may cause adverse interactions with some drugs so you should review any use of it with your medical resources.

6 thoughts on “Licorice – Glycyrrhiza

    • Dan, this 1968 report was for someone taking 36gm x 3 = 108gm / day for 6 years. The recommended approach is 2.5 grams in warm milk once a day. If after 6 months there have been no effect — then discontinue…

      Again, it does interact with various drugs — so if you are doing any prescription drugs, your MD should OK it’s use.

      Most CFS are low on cortisol, so increasing it’s half life has a beneficial side effect of raising cortisol levels. See and

      As always consult your knowledgeable medical professional before starting any supplements.

  1. Pingback: Where do I go from here… Part #1 | CFS Remission

  2. Pingback: Dealing with repopulation of bad bacteria | CFS Remission

  3. Pingback: First Survey Results on Herbs | CFS Remission

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s