My earlier post on psoriasis also appears to apply to  psoriasis arthritis.  This opens up the question of other forms of arthritis and the microbiome. A few example articles

• The microbiome and rheumatoid arthritis [2011]
• A gut feeling about arthritis.[2013]
  • High Prevotella genus levels
  • Reduced Bacteroides
• Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis.[2013]
• Microbiome and mucosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity.[2014]
  • Porphyromonas gingivalis overgrowth
  • Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis.[2012]
• Analysis of fecal Lactobacillus community structure in patients with early rheumatoid arthritis.[2013]
  •  “a potential relationship between Lactobacillus communities and the development and progression of rheumatoid arthritis.” – in other words avoid Lactobacillus (may be due to it killing E.Coli)
• Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis. [2014]
  • Lactobacillus casei improves symptoms
  • Study found L. Casei increases Prevotella [2014]
  • Lactobacillus species are higher(associated) with more cavities in some populations [2014]
  • Lacotbacillus brevis inhibits Prevotella biofilm formation [2013]
• The role of the microbiome in rheumatic diseases.[2013]
  • Fetal Transplants discussed
• The microbiome, autoimmunity, and arthritis: cause and effect: an historical perspective.[2012]

There is not enough to develop a good model — the KISS model would be:

• Bad periodontal bacteria successfully populate the gut resulting in arthritis

Suggested Course of Treatment from that model:

• Oral Probiotics (consider taking a different one of each after each meal (after brushing teeth)
• • Now Foods OralBiotic on Amazon (60 capsule for $14) – Streptococcus salivarius BLIS K12
  • Oragenics Evora Plus Probiotic on Amazon (30 mints for $16) – Streptococcus oralis, Streptococcus uberis, and Streptococcus rattus
  • [Very Suspect]Swanson Oral Probiotic: Blis K12® S. salivarius, L. rhamnosus, L. plantarum, L. reuteri, L. paracasei, L. salivarius
    • This one was a delight to find because it contains L.Reuteri which is hard to find in a probiotic.
    • On the negative side, it seems that some Lactobacillus are good and some are bad for this condition and since stains are rarely given on anything containing Lactobacillus, it may be best to assume all are suspect of making it worst.
• Mouth Rinse using EDTA or NAC dissolved in water (breaks down biofilm)
  • Consider doing nasal cleaning with traditional saline solution PLUS EDTA or NAC dissolved in the solution.
• Reduce use of general Lactobacillus bacteria (yogurt etc)
• No herbs could be found on PubMed effective against Porphyromonas or Porphyromonas gingivalis or Prevotella
  • Horseradish (Armoracia rusticana) appears effective [2013], it also inhibits biofilms [2012]
  • Omega 3 and Omega 6 [2013] – eat fish a lot, or open capsules and rinse around in your mouth, then swallow (remember the goal is to address the reserve of this bacteria — i.e. the mouth)
    • Take an EDTA capsule immediately after the meal
  • For Antibiotics choices, see [1998] and the Genome Project. As of [2014] the science is “Different aerobic and anaerobic bacterial species were either resistant against a number of antibiotics or showed high minimal inhibitory concentrations against clinically relevant antibiotics.” This same article suggest that biofilms are a major player for resistance.
• Probiotic supplements (NOT Lactobacillus) in the hope that they will out compete the bad bacteria.