In my last post I stumbled on a PubMed article that appears to identify two probiotics that should reduce histamines:
- “We found that mice that received GG and PJS[Propionibacterium freudenreichii] exhibited significantly lower numbers of intestinal mast cells compared with control mice.”
The implied logic is simple, less mast cells in the intestines, the less histamines to release. When I had visited this item before, I was searching directly for histamines and probiotics. Changing the search to probiotics and mast cells I came up with 47+ articles. “Accordingly, subsets of patients with IBS show higher numbers and an increased activation of mucosal immunocytes, particularly mast cells. “
“Although the effect of probiotics on allergic responses is different depending on the strains, doses, and experimental protocols, animal studies generally …reduction of degranulated mast cells,” 
From these articles, I found the following interesting reports:
- Extracellular vesicle-derived protein from Bifidobacterium longum alleviates food allergy through mast cell suppression .
- Effects of probiotic Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS supplementation on intestinal and systemic markers of inflammation in ApoE*3Leiden mice consuming a high-fat diet .
- Probiotic Lactobacillus rhamnosus downregulates FCER1 and HRH4 expression in human mast cells .
- “Oral treatment with both viable and heat-inactivated Lact. sakei probio 65 (isolated from Kimchi ) inhibits skin inflammation and AD-like skin lesions, as well as mast cell activation.”
- Systemic effects of ingested Lactobacillus rhamnosus: inhibition of mast cell membrane potassium (IKCa) current and degranulation. “the systemic effects of certain candidate probiotics may include mast cell stabilization and such actions could contribute to the beneficial effect of these organisms in allergic and other inflammatory disorders.”
- “numbers of total leukocytes and mast cells in BALF induced by OVA challenge were significantly suppressed by oral administration of LFK.[lysed Enterococcus faecalis FK-23 (LFK) orally for 28 days] 
- “L. casei protected from anaphylaxis and arthritis, and inhibited mouse mast cell and human basophil activation.”
- “that high doses of non-pathogenic E. coli bacteria can function as a strong, direct inhibitor of MC [Mast Cell] degranulation.”  – likely Mutaflor, i.e. E.Coli Nissle 1917
Following on to the prior post, we end up with the following being a group of mast cell inhibitors that appears to be fine to take together.
- Mutaflor (E. coli Nissle 1917) x Securil (Propionibacterium freudenreichii) x Culturelle (Lactobacillus rhamnosus GG) x Yakult (Lactobacillus Casei)