lassesen 5:23 am on November 30, 2015  

Decreasing Adlercreutzia

Low levels are associated with other conditions.

For updated information see Microbiome Prescription

DataPunk.Net Data

Very little…

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PubMed Data

There are about 17+ articles on PubMed.

  • Disease Risks:
    • “Adlercreutzia was also decreased in inflammatory bowel disease  cases compared to controls but was at similar levels in non-responders and responders. ” [2016] Thus high levels suggests reduced risk of evolving to IBD.
    • “control group showed increased abundance of Parabacteroides, Adlercreutzia and Prevotella genera. compared to Multiple sclerosis ” [2016] Thus high levels suggests reduced risk of evolving to MS
    • “primary sclerosing cholangitis  was further characterized by decreased abundance of Adlercreutzia equolifaciens” [2017] high levels suggests reduced risk
    • “Colorectal adenoma subjects had … lower abundance of Adlercreutzia compared to controls. ” [2017] high levels suggests reduced risk
  • Diet:
    • “Bacteroides spp., Coriobacteriaceae spp. and Adlercreutzia spp. were increased in nonresponders, responders 101, and IBS-D and- M patients, respectively, following a diet low in fermentable carbohydrates( low-FODMAP ).” [2016]
    • “Daidzeins are isoflavonoids commonly found in soybeans that are
      metabolized into the metabolite equol by specific gut microbes, such as the aptly named Actinobacteria species,” [2016] [2012]
    • “Adlercreutzia and Lactobacillus which were found to be enriched in Low Fat” [2016] compared to ” high-fat (40 E% saturated fat, HF) control diet, or heat-treated high-fat (200 °C for 10 min, HT) diet, for 8 weeks.”
  • Prebiotics:
    • “In contrast, Adlercreutzia, Odoribacter, and Coprococcus were significantly more abundant in microcrystalline cellulose group M,”
  • Probiotics:
    • ” there was significantly lower … Adlercreutzia equolifaciens following both interventions( the L. casei Zhang or vitamin K2 ) compared to the model group. ” [2017]
    • “a fermented dairy product (FDP) fortified with Bifidobacterium animalis subsp. lactis… Increased lactose fermenting taxa included Slackia isoflavoniconvertens and Adlercreutzia equolifaciens; ” [2017]
  • Antibiotics:
    • “Ten OTUs indicating fluoroquinolone treatment were associated with Blautia, Subdoligranulum, Adlercreutzia, Clostridium and Ruminococcus.” [2014]

Bottom Line

  • Do not do a low-FODMAP diet
  • No soy (it’s a food source)
  • Vitamin K2 supplementation
  • Lactobacillus Casei probiotics
  • E.Coli Probiotics (Mutaflor, Symbioflor-2)
  • No Bifidobacterium animalis subsp. lactis probiotics
  • No fluoroquinolone antibiotics