While these studies are not dealing with CFS patients — they are interesting because some of the conclusions / observations may be relevant.
Feed a cold (viral infection), starve a fever (bacterial infection)
This was reported in a NewScientist news story on 2002. “Dutch scientists have found that eating a meal boosts the type of immune response that destroys the viruses responsible for colds, while fasting stimulates the response that tackles the bacterial infections responsible for most fevers.” This was also reported in Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation [Cell Sept 2016] – so both human and mice studies found the same thing.
Impact for CFS:
- If you have a flare — then one time:
- fast for 12 hours
- take food (or capsules) high in glutamine amino acid (i.e. milk, meat, nuts)
If fasting make you better, faster than food then a bacterial infection is likely a significant factor.
If food makes you better, faster than fasting, then a vial infection is likely a significant factor. – for example a viral re-activation.
Bacteria lurking in blood could be culprit in countless diseases
This NewScientist Sept 14, 2016 article reported “A molecule made only by bacteria has been found to change blood proteins in a way that is common to a score of “non-infectious” conditions, from heart attacks to Alzheimer’s disease….. They need iron ions to grow, and iron is bound up by proteins that keep free ions at vanishingly low levels in our blood.”
What is very surprising is the impact “Just one molecule of lipopolysaccharides (LPS). mixed with 100 million fibrinogen molecules was enough to trigger these changes (Journal of the Royal Society Interface, doi.org/bqh5).” Fibrinogen can lead to thick blood.
In terms of treatment, “There could potentially be a link to cancer, too. Inflammation is seen in cancer and the anti-inflammatory drug aspirin is known to lower cancer rates. The pill is also reported to bind free iron, which together may suggest bacteria have a hidden role in this disease too.”
Aspirin has been a bit of a mystery drugs — I recall reading several years ago, a Scientific American article on Aspirin stating that they do not understand how aspirin works. “Although many of ASA’s pharmacological actions are related to its ability to inhibit prostaglandin and thromboxane biosynthesis, some of its beneficial therapeutic effects are not completely understood.” 
During my second remission, I took the maximum daily dosage of aspirin for 10 days to see if hypercoagulation was indeed part of CFS. I made a dramatic improvement. My MD was now willing to explore hypercoagulation. In hindsight, aspirin may have been doing multiple things that resulted in the improvement.
- The influence of non-steroidal anti-inflammatory drugs on the gut microbiome .
- “The bacterial composition of the gut varied with the type of NSAID ingested.”
- “Four OTUs (Prevotella species, Bacteroides species, family Ruminococcaceae, and Barnesiella species) discriminated aspirin users from those using no medication”
- Non-steroidal anti-inflammatory drugs may modulate the protease activity of Candida albicans .
- “In other hand, aspirin seems to reduce the secretion of aspartyl-proteases -related pathogenic behavior of candidal biofilms.”
- Aspirin-associated iron loss: an anticancer mechanism even in the short term?
- Antiviral activity of aspirin against RNA viruses of the respiratory tract – an in vitro study 
- “These data demonstrate a specific antiviral activity of aspirin against influenza A virus and HRV. The mode of action against rhinoviruses is still unknown and requires further investigation, as does the possibility of aspirin being effective in vivo to treat the common cold.”
- Aspirin inhibits hepatitis C virus entry by downregulating claudin-1. 
- Aspirin attenuates cytomegalovirus infectivity and gene expression mediated by cyclooxygenase-2 in coronary artery smooth muscle cells. 
- Aspirin inhibits a murine viral infection.
- “it is possible that aspirin has previously unrecognized therapeutic effects in various clinical situations, such as in viral infections (when used as an antipyretic agent) and in atherosclerosis (when used as an antiplatelet agent).