Probiotics: Nature’s Bounty Probiotic 10

A reader (with Crohn’s Disease, not CFS) asked me about this probiotic — especially as it is just $20 at Costco. The probiotic lists all of the strains (finer identification than species) – which is a very good thing. You know better what you are getting (in terms of expected health impacts).

nature

This is NOT recommended for CFS because it will reduce E.Coli (which are very low to non-existent with CFS). With Crohn’s disease there is an overgrowth of E.Coli.

So what to expect?

Lactobacillus plantarum 299v (DSM 9843)

Lactobacillus paracasei DSM 13434 (8700:2)

  • “In conclusion, intake of the probiotic strains Lactobacillus plantarum HEAL 9 (DSM 15312) and Lactobacillus paracasei 8700:2 (DSM 13434) reduces the risk of acquiring common cold infections.”[2011]
  • “Our findings indicate a therapeutic potential of oral administration of a combination of probiotics and provide a more complete understanding of the host-commensal interactions that contribute to beneficial effects in autoimmune diseases.” [2010]
  • Lactobacillus paracasei 8700:2 (DSM 13434)

Lactobacillus plantarum DSM 15312 (HEAL9)

  • “In conclusion, intake of the probiotic strains Lactobacillus plantarum HEAL 9 (DSM 15312) and Lactobacillus paracasei 8700:2 (DSM 13434) reduces the risk of acquiring common cold infections.”[2011]
  • “Our findings indicate a therapeutic potential of oral administration of a combination of probiotics and provide a more complete understanding of the host-commensal interactions that contribute to beneficial effects in autoimmune diseases.” [2010]
  • Academic Paper [2015]

Lactobacillus bulgaricus lb-87

  • “In his study, both Salmonella sp. and E. Coli are inhibited when mixed with GLB44 invegetable juice.[9] ” Wikipedia
  • No PubMed studies

Lactobacillus brevis LBR-35

Lactobacillus salivarius LS-33

  • “Ratios of Bacteroides-Prevotella-Porphyromonas group to Firmicutes belonging bacteria, including Clostridium cluster XIV, Blautia coccoides_Eubacteria rectale group and Roseburia intestinalis, were significantly increased (p ≤ 0.05) after administration of Ls-33. The cell numbers of fecal bacteria, including the groups above as well as Clostridium cluster I, Clostridium cluster IV, Faecalibacterium prausnitzii, Enterobacteriaceae, Enterococcus, the Lactobacillus group and Bifidobacterium were not significantly altered by intervention.” [2013]
  • Lactobacillus salivarius Ls-33 and Bifidobacterium infantis 35624 preferentially induced IL-10.” [2011]

Lactobacillus paracasei LPC-37

  • “L. paracasei Lpc-37 and B. lactis 420 are able to colonize the intestine transiently.” [2008] i.e. does not stay
  • “The use of probiotic cultures significantly increased the availability of calcium (~2.5%), phosphorus (~6%), and magnesium (~18%).” [2014]

Lactobacillus acidophilus LA-14

  • “Trends toward significant changes in immunoglobulin serum concentrations compared with controls (P<0.1) were found for six out of the seven probiotic strains.” [2008]
  • “Consumption of L. acidophilus La-14, L. rhamnosus HN001 in combination with bovine lactoferrin leads to vaginal detection; even 1 week after consumption was stopped.” [2015]
  • “L. acidophilus La-14 produces bacteriocin active against Listeria. monocytogenes ScottA… L. acidophilus La-14 shows a good resistance to several drugs and may be applied in combination for therapeutic use.” [2011]

Bifidobacterium lactis BL-04 (ATCC SD5219)

  • Monograph from supplier
  • “Trends toward significant changes in immunoglobulin serum concentrations compared with controls (P<0.1) were found for six out of the seven probiotic strains.” [2008]
  • “The pollen season induced a reduction in Bifidobacterium, Clostridium and Bacteroides which could not be prevented by the probiotic intervention… Fecal IgA was increased in the placebo group during the pollen season; this increase was prevented by the probiotics ” [2009]
  • “The risk of an upper respiratory illness episode was significantly lower in the Bl-04 group ” [2014]

Lactobacillus casei Lc-11 (ATCC SD5213)

  • Excellent inhibition of E.Coli,  Good inhibition of Salmonella typimurium, Straphylococcus aureus, Listeria monocytogeners
  • Produces only L(+) Lactic acid (no D-Lactic) [2008]
  • No pub med studies

Bottom Line – Not for CFS Patients

Why? The answer is simple — many of the above strains inhibits or kill E.Coli. E.Coli is very low or non-existent with CFS patients.  This probiotic may make a bad situation worst.