There are no official tests for CFS — but there are a ton of markers!

I often have read on the web that there is no test for CFS. This is very incorrect — there is no official test for CFS nicely bundled up.  “No current diagnostic tool or method has been adequately tested to identify patients when diagnostic uncertainty exists.”[2014]  What we find in the literature are many tests available to confirm CFS/ME when symptoms presents.

This post reviews where there have been a strong association of abnormal laboratory results to CFS/ME patients. These tests can often be used to confirm that the diagnosis is correct. For example: is TGF-β elevated and resistin lower?  etc.  In terms of microbiome results from low or no lactobacillus, low or no bifidobacteria, low or no akkermansia muciniphila, low or no E.Coli.

My Own Favorite Ad-Hoc Markers

From uBiome:

  • Low or no Lactobacillus
  • Low or no Bifidobacteria
  • Low or no E.Coli
    • Not directly reported, but it parent is: Enterobacteriaceae which will be NOT listed in results, or at something like 2% of the reference group
  • Low or High Akkermansia (parent is Verrucomicrobiaceae)

Bottom Line

Yes, there is testing that can be used to increase the certainty of a CFS/ME diagnosis (or exclude it — which should lead to further testing).