This is a rare bacteria occurring in only 4.2% of all uBiome samples. Any bacteria genus < 5% I view as a probable overgrowth that should be reduced as a secondary target.

“Cronobacter spp. were isolated from:

• 15% of 33 spice and herb samples and
• 3% of 36 taste foods,
•  fresh vegetables were detected in 12% of field vegetables and 13% of hydroponic vegetables.
• shredded vegetables were detected from 44% of 9 samples,” [2017]

For updated information see Microbiome Prescription

DataPunk.Net Data

INHIBITED BY

• Pomegranate ellagitannins [parent – Enterobacteriaceae –]
• Ketogenic diet

ENHANCED BY

• Aspartame [parent – Enterobacteriaceae –]

PubMed Data

There are 750+ studies on PubMed. Many studies deal with contaminated milk formula in China. This dive is not fully done yet.

• Disease:
  • associated with neonatal diseases (sepsis, meningitis, necrotizing enterocolitis...) urosepsis and bacteremia” [2016]
  • Cronobacter sakazakii infection alters serotonin transporter and improved fear memory retention in the rat [2015].
• Diet:
  • “Ketogenic diet poses a significant effect on imbalanced gut microbiota… decreases” [2017]
  • ” tea polyphenols  had an effective bactericidal effect against C. sakazakii,” [2016]
  • “. Both strains were susceptible to thymol, carvacrol, thymoquinone, p-cymene, linalool, camphor, citral, eugenol, and trans-cinnamaldehyde as well as cinnamon, lemongrass, oregano, clove, and laurel essential oils; their minimum inhibitory concentrations varied between 0.1 and 2.0 mg/mL” [2014]
  • “, combinations of commercial Nisaplin and the food additive citric acid reduced C. sakazakii numbers markedly in infant formula within the same 3 h period. ” [2017]
  • “Citral (lemon oil) substantially reduced the adhesion and invasion of C. sakazakii to Caco-2 cells and decreased bacterial survival and replication ” [2017]
    • Antimicrobial Activity and Possible Mechanism of Action of Citral against Cronobacter sakazakii [2016].
• Probiotics:
  • “Lactobacillus plantarum NTU 102 from homemade Korean-style cabbage pickles…. was found to be effective against V. parahaemolyticus BCRC 12864 and Cronobacter sakazakii BCRC 13988. ” [2017]
  • “the greatest co-aggregation abilities were observed for Bifidobacterium bifidum W23, Lactobacillus plantarum W21 and Lactobacillus rhamnosus W71….” [2017]
  • [Lactobacillus rhamnosus GG inhibits Cronobacter-induced meningitis in neonatal rats] 2015.
• Antibiotics:
  • “Cronobacter strains identified in this study were not susceptible to third-generation cephalosporins, aminoglycoside, and/or trimethoprim-sulfamethoxazole. ” [2017]
  • “showed very high resistance to ampicillin, amoxicillin, tetracycline, chloramphenicol and sulfamethoxazole/trimethoprim.” [2015]

Bottom Line

Avoid

• shredded vegetables

Take

• Vitamin C
• Lactobacillus plantarum
•  Bifidobacterium bifidum ,
• Lactobacillus rhamnosus
• Nisaplin (from  Lactococcus lactis )
• Ketogenic diet
• Tea
• Cinnamon,
• Lemongrass,
• Oregano,
• Clove