With the model, there may be a lack of metabolites which will vary from person to person. The response will further vary according to DNA. A reader asked specifically about how to treat muscle weakness that often occurs after stress.

In this post, I will attempt to identify treatment options for muscle weakness

The PubMed Literature

• ” Vitamin B6 was low in half and thiamine was low in all patients when obtained before supplementation. ” [2018]
• GLUTAMINE AS AN AID IN THE RECOVERY OF MUSCLE STRENGTH: SYSTEMATIC REVIEW OF LITERATURE] [2015].
  • “of 661 articles, six relevant studies were identified. The study participants in glutamine  isolation evaluation did not suggest changes between the groups, only an improvement in the perception of muscle weakness“
• Potassium [2004]
  • “Very low serum potassium levels (≤ 2.5 mmol/L) can lead to muscle necrosis, paralysis, cardiac arrhythmias, and impaired respiration, which can be life-threatening. ” [2015]
• “there may also be an implication of low vitamin D status in bone loss, muscle weakness ” [2014]
  • Vitamin D: key to muscle and bone strength, independence. A deficiency in vitamin D could impair your mobility and activities of daily living[2013].

  • Reversible muscle weakness in patients with vitamin D deficiency.[1997]

• Four key nutrients decrease the risk of bone and muscle degeneration. The interaction of calcium, vitamin D, phosphorus, and protein affect musculoskeletal health in aging adults [2014].
• “L-Carnitine (LC) administration has been recommended for specific indications in dialysis patients, including epoetin-resistant anemia, intradialytic hypotension, cardiomyopathy, fatigue, muscle weakness, and exercise performance; it may ameliorate insulin resistance, inflammation, and protein wasting. ” [2013]
• “High quality evidence from randomised controlled trials shows that short- and medium-term creatine treatment increases muscle strength in muscular dystrophies. ” [2011]
  • “Of the 8 hypocarnitinemic patients, 3 complained of muscle weakness, and their symptoms disappeared during carnitine supplementation. ” [2008]
  • Creatine for treating muscle disorders. [2007]

  • Effects of creatine supplementation on muscle weakness in patients with rheumatoid arthritis [2000]

  • “Carnitine supplements increase the tolerance of muscle to physical
    exercise, and help prevent exercise induced muscle pain and muscle weakness [11]. A dose equivalent to 250 mg carnitine/day is proposed ” [2005]
• “Germanium-containing dietary supplements became popular in the 1970s in Japan and later in other countries, as elixirs for certain diseases (e.g., cancer and AIDS). Germanium is not an essential element. Its acute toxicity is low. However, …. Other adverse effects were anemia, muscle weakness, and peripheral neuropathy” [1997]

Bottom Line

Avoid:

• Germanium supplements
• Red rice yeast
• Statins

Take

• Creatine – typically 20 g per day for 5 days) [1995] 3-5 g/day [Src]
• L-Carnitine  – 250 mg/day  up to 2 g of l–carnitine every 12 h. [2004]
• Thiamine (Vitamin B1) – “. All (IBD) patients were assigned to receive high doses of thiamine orally. Depending upon the body weight of each patient,
  dosage ranged from 600 mg/day (60 kg) to 1,500 mg/day (90 kg)” [2013]
• Pyridoxine (Vitamin B6) – “120 mg vitamin B6; “[1999] [1983]
• Vitamin D3
• Potassium (One banana = 422 mg –  it is thought that 1600 to 2000 mg is adequate [Mayo Clinic – includes list of potassium rich food]
• CoQ10 – if statins or red rice yeast contributed

This is an education post to facilitate discussing this with your medical professionals. It is not medical advice for the treatment of any condition. Always consult with your medical professional before doing any  changes of diet, supplements or activity. Some items cites may interfere with prescription medicines.