This is a review of recent studies recorded on PubMed. The focus is on new information – so studies reporting prior information will rarely be mentioned.
- The effects of warm water immersion on blood pressure, heart rate and heart rate variability in people with chronic fatigue syndrome[2018].
- Temporary relief.
- “Chronic fatigue syndrome (CFS) is a central sensitisation syndrome with abnormalities in autonomic regulation of blood pressure (BP), heart rate (HR) and heart rate variability (HRV).”
- Cerebral blood flow and heart rate variability predict fatigue severity in patients with chronic fatigue syndrome. [2018]
- Dry eye syndrome and the subsequent risk of chronic fatigue syndrome-a prospective population-based study in Taiwan.
- 2x greater risk of CFS
- Chronic fatigue syndrome patients have alterations in their oral microbiome composition and function.
- “CFS patients had a higher relative abundance of Fusobacteria compared with healthy controls. Further, the genera Leptotrichia, Prevotella, and Fusobacterium were enriched and Haemophilus, Veillonella, and Porphyromonas were depleted in CFS patients compared to healthy controls. “
- Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons [2018].
- “Results support the notion that specific microorganisms interact with some ME/CFS symptoms and offer promise for the therapeutic potential of targeting gut dysbiosis in this population. Streptococcus spp. are not the primary or sole producers of D-lactate. Further investigation of lactate concentrations are needed to elucidate any role of D-lactate in this population”
- 400 mg of erythromycin twice daily
- Visual Aspects of Reading Performance in Myalgic Encephalomyelitis (ME)[2018].
- “vision-related reading difficulty belongs to a class of measureable symptoms for ME/CFS patients.”
- The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome [2018].
- “LncRNAs NTT, MIAT and EmX2OS levels were found to be significantly elevated in ME/CFS patients as compared with healthy controls. Furthermore, NTT and EmX2OS levels increased with disease severity. “
- Multidisciplinary rehabilitation treatment is not effective for myalgic encephalomyelitis/chronic fatigue syndrome: A review of the FatiGo trial[2018].
- Cognitive-behavioural therapy for chronic fatigue syndrome: neither efficacious nor safe[2018].
- Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case-Control Study[2018].
- Differentiating Multiple Sclerosis from Myalgic Encephalomyelitis and Chronic Fatigue Syndrome [2017].
- “Those individuals with ME or CFS reported significantly more functional limitations and significantly more severe symptoms than those with MS.”
Bottom Line
It was nice reading of success addressing the lactic acid aspect of CFS with antibiotics (erythromycin – a macrolide) on patients with high streptococcus count. It was the coming together of multiple threads — if you want to understand better or get a better background, see these posts: