Microbiome and Iron, Calcium, Phosphate, Zinc…

However, Bifidobacteriaceae are capable of binding iron in the large intestine, thereby limiting the formation of free radicals synthesized in the presence of iron, and thus reducing the risk of colorectal cancer. Animal studies have revealed that supplementation with probiotics, prebiotics and synbiotics has a significant effect on bone calcium, phosphate and bone metabolism. The dynamic interaction between microbiota and zinc was shown. Human studies have provided evidence of the influence of probiotic bacteria on parathormone, calcium and phosphate levels and thus on bone resorption. Recent studies have produced new information mainly on the impact of the intestinal bacteria on the metabolism of calcium and iron. From a scientific perspective, the most urgent fields that remain to be investigated are the identification of all human gut microbes and new therapies targeting the interaction between intestinal bacteria and minerals.

Association between the gut microbiota and mineral metabolism. [2018]

In this post, I will try finding the studies and further information.

Bottom Line

The available literature suggests that Lactobacillus and Bifidobacterium are dominate player for calcium levels. Since these are much higher in children than adults, this would assist in bone growth by providing the needed calcium. This appears to extend to other minerals such as zinc, copper, phosphorus in a similar manner.

Both Lactobacillus and Bifidobacterium decrease with old age and may account for calcium /bone loss issues. ” The presence of the BifidobacteriumFaecalibacteriumBacteroides group, and Clostridium cluster XIVa decreased with age up to 66-80 years of age,  “[2019]

Low levels of one of more of theses would hint towards insufficient of these, or a bad balance with them. High levels of one or more would hint towards a surplus of these, or a bad balance with them.