Tonight I found two gems that I wish to share
“The major effects of stress on gut physiology include:
- alterations in gastrointestinal motility;
- increase in visceral perception;
- changes in gastrointestinal secretion;
- increase in intestinal permeability;
- negative effects on regenerative capacity of gastrointestinal mucosa and mucosal blood flow; and
- negative effects on intestinal microbiota.
Mast cells (MC) are important effectors of brain-gut axis that translate the stress signals into the release of a wide range of neurotransmitters and proinflammatory cytokines,”[2011]
Histamine released from Mast Cells cause many of the symptoms of a Jarisch-Herxheimer reaction. So I was about to do a quick review of PubMed for candidates that reduced Mast Cell release:
- Lactobacillus GG (LGG) [2014] – strong impact – Commercial Probiotic: Culturelle
- L. salivarius HMI001 [2012]
- L. casei Shirota (LCS) [2012]
- Lactobacillus plantarum depends on the specific strain — if not known, avoid
At this point of browsing PubMed, I discovered the 2014 article (World J Gastroenterol. 2014 Aug 28; 20(32): 11023–11032.) and it distracted me because it had some nice tables based on recent literature which warrants reposting.
Recommendations for probiotic use from [2014]
Clinical condition | Effectiveness | Organism |
Diarrhea |
||
Infectious-adult-treatment | A | Saccharomyces boulardi, LGG |
Infectious-childhood- treatment | A | LGG. Lactobacillus reuteri |
Prevention of infection | B | S. boulardii, LGG |
Prevention of AAD | A | S. boulardii, LGG, L. casei, L. bulgaricus, S. thermophilus |
Treatment of recurrent CDAD | B | S. boulardii, LGG |
Prevention of CDAD | B | LGG, S. boulardii |
IBD | ||
Pouchitis |
||
Preventing and maintaining remission | A | VSL#3 |
Induce remission | C | VSL#3 |
Ulcerative colitis |
||
Inducing remission | C | Escherichia coli Nissle, VSL#3 |
Maintenance | C | E. coli Nissle, VSL#3 |
Crohn’s | C | E. coli Nissle, S. boulardii, LGG |
IBS |
B | Bifidobacterium infantis |
IBS | C | Bifidobacterium animalis, VSL#3, Lactobacillus plantarum |
Immune response | A | LGG, Lactobacillus acidophilus, L. plantarum, Bifidobacterium lactis, Lactobacillus johnsonii |
Allergy |
||
Atopic eczema assoc. with cow milk allergy | ||
Treatment | A | LGG, B. lactis |
Prevention | A | LGG, B. lactis |
Radiation enteritis | C | VSL#3, L. acidophilus |
Vaginosis and vaginitis | C | L. acidophilus, LGG, L. reuteri |
Reproduced with permission from reference Floch et al[31].
- An ‘‘A’’ recommendation is based on strong, positive, well-conducted, controlled studies in the primary literature, not abstract form;
- A ’‘B’’ recommendation is based on positive, controlled studies but the presence of some negative studies;
- A ‘‘C’’ recommendation is based on some positive studies.
- IBD: Inflammatory bowel disease;
- LGG: Lactobacillus GG;
- S. boulardii: Saccharomyces boulardii.