A reader asked for what probiotics to use for dry-mouth or hyposalivation or Xerostomia.. “is often seen as a side effect of many types of medication, and associated with Sjögren’s syndrome. Over 500 medications produce xerostomia.
- “Probiotic intervention reduced the risk of high yeast counts by 75% , and the risk of hyposalivation by 56%. Thus,probiotic bacteria can be effective in controlling oral Candida and hyposalivation in the elderly.”  [Full article] – “107 cfu (colony-forming units)/g of each of the probiotic strains, L. rhamnosus GG (ATCC 53103), L. rhamnosus LC705, and Propionibacterium freudenreichii ssp shermanii JS (Valio Ltd, Joensuu, Finland) “
- “Cluster I is made up 76% of subjects with hyposalivation …have higher.. genera Veillonella, Dialister, Prevotella, Fusobacterium, and Streptococcus.”
- “species of Candida tropicalis and Parapsilosis were more detected in the primary Sjogren’s syndrome “
- “the primary Sjogren’s syndrome subjects displayed an increased frequency of C.albicans, Staphylococcus aureus, enterics, and enterococci”
- “These results suggest that particular Candida species are involved in the pathogenesis of oral mucosal disorders in patients with xerostomia.”
So which probiotics?
If you live in Finland (or planning to visit soon), you may be able to get the one probiotic cited above.
- “given 1 lozenge containing 2 strains of the probiotic bacterium Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) … There was a statistically significant reduction in the prevalence of high Candida counts in the probiotic group but not in the placebo group,”
- “consumption of the probiotic Yakult LBz(®) (Lactobacillus casei and Bifidobacterium breve)…showed a statistically significant reduction (p<0.05) in Candida prevalence (from 92.9% to 85.7%), in CFU/mL counts of Candida and in the number of non-albicans species after consumption” 
- “the probiotic Yakult LB® for 20 days, showed a significant reduction in Candida prevalence (46%) and mean Candida CFU/mL counts (65%).
Oral Probiotic tablets usually contain S. salivarius K12, it and M18 appears to have no explicit significant impact on Candida. It is unclear if they will have impact on Dry Mouth (so they are worth a try if the L.Reuteri longenze or L.Reuteri Oral Probiotics are not easily obtainable).
- “S. salivarius Strain K12, the prototype S. salivarius probiotic, originally introduced to counter Streptococcus pyogenes infections”
- “The study included 67 salivary and subgingival lactobacilli of 10 species…but none inhibited Candida albicans.”
Yakult LB is a good candidate (two studies) if you can get it (it is sold in Brazil). Regular Yakult (or DanActive) and Bifidobacterium breve may be an alternative
The following contain mainly L.Reuteri:
- BioGaia Chewable (Chewable Tablets) L.Reuteri probiotic
- Nova Diet Oraldiet
Propionibacterium freudenreichii is only available in Nutricology, Securil
L.Reuteri included as part of a mix in these Oral Probiotics
- Powerful Oral Probiotics with 7 STRAINS of beneficial bacteria
- PRO-Dental: Probiotics for Oral & Dental Health
Tradition Guidance for dry mouth should also be checked/tried, like this post. Many of the items are already the norms for CFS patients, i.e. no coffee or alcohol….
Other’s have distinctive CFS/IBS/FM versions:
- “sugar-free chewing gum” — all of the fake sugars are worse than real sugar for the microbiome. Use Mastic Gum instead.
- “a hard candy into your mouth to stimulate your saliva glands and aid production.”
- Use spezzatina instead (pure licorice)
- xylitol washwash is a strongly not recommended.