POTS co-morbid with CFS. It turns out that several vaccines that have a ‘vaccine syndrome’ which included POTS.

• Orthostatic intolerance and postural tachycardia syndrome as suspected adverse effects of vaccination against human papilloma virus [2015].
• [Neurologic Complications in HPV Vaccination] [2015].  “delayed manifestation of cognitive dysfunction in the post-vaccinated girls has attracted attention. The symptoms include memory loss and difficulty in reading textbooks and/or calculation.”
• Postural tachycardia syndrome after vaccination with Gardasil.[2010]
• Paroxysmal supraventricular tachycardia precipitated by pertussis vaccine [1983].
• [Associated ventricular tachycardia and auricular fibrillation after anticholera vaccination][1973].
• .[Post-vaccinal encephalopathy syndrome] [1957].
• [POST-VACCINAL SCHOELEIN-HENOCH SYNDROME. PRESENTATION OF 3 CASES, 2 OF WHICH PRESENTED AFTER ANTIPOLIOMYELITIC VACCINATION].[1965]
• [Neurological complications after influenza vaccination (author’s transl)]. [1977]
• Neurological complications of swine influenza vaccination. [1982]

This is not that surprising, because the vaccine promotes an immune response which likely includes alteration of the microbiome.

“..a trend for reduced gamma-interferon in the CFS-vaccine group… Polio vaccination was not found to be clinically contraindicated in CFS patients, however, there was evidence of altered immune reactivity and virus clearance.” [1997]

The following illustrates how adverse effects are often deem “not significant” in a population [2011].

“RESULTS:

VAERS received 294 reports of AEs in pregnant women who received 2009-H1N1 vaccine: 288 after inactivated and 6 after the live attenuated vaccines. Two maternal deaths were reported. Fifty-nine women (20.1%) were hospitalized. We verified 131 pregnancy-specific outcomes: 95 spontaneous abortions (<20 weeks); 18 stillbirths (≥20 weeks); 7 preterm deliveries (<37 weeks); 3 threatened abortions; 2 preterm labor; 2 preeclampsia; and 1 each of fetal hydronephrosis, fetal tachycardia, intrauterine growth retardation, and cleft lip.

CONCLUSION:

Review of reports to VAERS following H1N1 vaccination in pregnant women did not identify any concerning patterns of maternal or fetal outcomes.”