My last post on lactobacillus rhamnosus was back in 2012, I recently found some new interesting articles on PubMed, so time for an update. Over the weekend, I had a run to Canada to pick up a supply of Mutaflor for my wife (Crohn’s Disease) and spotted Jamieson probiotic for traveler’s diarrhea. They were 10 billion CFU of Lactobacillus Rhamnosus GG per capsule. Culturelle is the same strain and dosage — except for one thing, the wife did not react to Culturelle like she did to Jamieson’s!!! Jamieson’s had a much stronger effect and was 40% cheaper per capsules. I suspect that the Jamieson’s was a lot fresher (i.e. less time since manufacture) than Culturelle.

I have always found that probiotic intended to treat traveller’s diarrhea tend to be good candidate probiotic (if there is research backing it).

Latest Articles on Lactobacillus Rhamnosus

Probiotic Lactobacillus rhamnosus reduces organophosphate pesticide absorption and toxicity to Drosophila melanogaster[ 2016]. This hints that it may reduce MCS. My wife is trying an experiment with doing far infrared sauna followed by probiotics. It seems to be reducing her MCS sensitivity.
Probiotic lactobacilli: a potential prophylactic treatment for reducing pesticide absorption in humans and wildlife [2015]. “Probiotic Lactobacillus rhamnosus GR-1-supplemented yoghurt reduced the bioaccumulation of mercury and arsenic in pregnant women and children.” High mercury levels is associated with MCS
“The children and pregnant women in the study were found to have elevated blood levels of lead and mercury compared to age- and sex-matched Canadians. Consumption of probiotic yogurt containing 10(10) CFU Lactobacillus rhamnosus GR-1 had a protective effect against further increases in mercury (3.2 nmol/liter; P = 0.035) and arsenic (2.3 nmol/liter; P = 0.011) blood levels in the pregnant women, but this trend was not statistically significant in the children.” [2014]
Lectin-Like Molecules of Lactobacillus rhamnosus GG Inhibit Pathogenic Escherichia coli and Salmonella Biofilm Formation [2016].
“We present 4 cases of clinically diagnosed Food protein-induced allergic proctocolitis (AP) whose symptoms quickly and completely resolved with probiotic Lactobacillus rhamnosus GG (LGG) monotherapy. All 4 infants avoided any dietary restrictions. The range of time from probiotic initiation to symptom resolution was 7-28 days.” [2016]
Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model[2016].
“clinical and immunologic effect of probiotic and vitamin D supplementation … showed better clinical and immunologic response in children with allergic rhinitis.”[2016]
Lactobacillus rhamnosus GG Intake Modifies Preschool Children’s Intestinal Microbiota, Alleviates Penicillin-Associated Changes, and Reduces Antibiotic Use [2016].
“we demonstrated that twice-weekly treatment of sex steroid-deficient mice with the probiotics Lactobacillus rhamnosus GG (LGG) o…reduces gut permeability, dampens intestinal and BM inflammation, and completely protects against bone loss.” [2016]
“Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants.” [2016] – low butyrate was found in MCS individuals.
Lactobacillus rhamnosus GG inhibits the toxic effects of Staphylococcus aureus on epidermal keratinocytes [2014].

Jon 9:03 am on October 4, 2016

Great info as usual Ken.

If find LGG helps with histamine and also mood to a minor extent. Lately I have been taking it with L. gasseri (which Swanson thankfully have as a single strain product) to good effect. The thing I like about Culturelle (apart from responding well to it) is that you can buy a version without FOS.
Bernie 6:26 pm on October 4, 2016

Ken, where in Vancouver do you purchase your Mutaflor? I live here and haven’t been able to find anywhere that sells it.
- lassesen 7:47 pm on October 4, 2016
  
  I order it from Ontario and have it shipped to a cousin in Surrey
  - Bernie Standish 7:28 pm on October 20, 2016
    
    Thanks, Ken.
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Frank 4:00 pm on June 30, 2021

Hi,

I’m sorry I know this is an old post but I was wondering if you could help me with a few questions. Did Mutaflor help your wife get into remission and does it continue to work for her? Did your wife have Moderate Crohn’s? I have moderate to severe Crohn’s and no longer respond to the last of the available biological drugs. I’ve read about Mutaflor but never had the opportunity to speak to anyone on it. Thanks
- lassesen 4:54 am on July 1, 2021
  
  Yes — it put her into remission (defined as not needing any prescription drugs — to the surprise of her specialist). It still works wonders for her when ever there is an indication of a flare. She uses Symbioflor-2 (another e-coli probiotics that does not require cold storage in shipment) regularly and, while not as fast acting as mutaflor — it works similarly.
Frank 3:39 pm on July 1, 2021

Thank you for your reply Ken, was your wife’s Crohn’s pretty bad? I’m only asking because I’ve been through every biological drug available and I’m still inflammed, ulcerated and have had a few bowel resections and unfortunately I’ve got no other options left. I’m really hoping something like mutaflor might make the difference because it’s changing my Microbiome which is something I’ve never tried doing. Would it be possible to liaise with you via email? I’d really appreciate the help.