Decreasing Prevotella Buccalis

In Ian Lipkin et al 2017 study, high Prevotella Buccalis was reported (on average). [Index to all posts on Study] . Originally identified in 1982. It appears to be associated with periodontitis and the mouth.

tax

sigs-5098948-f1

  • “In a study of gut bacteria of children in Burkina Faso (in Africa), Prevotella made up 53% of the gut bacteria, but were absent in age-matched European children.”[2010]
  • “All Prevotella strains tested were susceptible to imipenem and amoxicillin/clavulanate, whereas 78.6% of the pigmented Prevotella species and 46.4% of the non-pigmented species were resistant to penicillin (MIC >0.5 μg/ml).” [2015]
  • ” lactamase production was observed for 1 Prevotella buccalis strain.” [2014]
  • “The beta-lactamase positive species Prevotella loescheii, Prevotella buccae, Prevotella buccalis and Actinomyces spp were recovered from the selective amoxicillin plates.” [1997]
  • “Cefpodoxime was found to be active at concentrations of less than or equal to 0.125 mg/l against Prevotella oralis, Prevotella buccalis” [1991]

Betalactamases (β-lactamases) are enzymes (EC 3.5.2.6) produced by bacteria (also known as penicillinase) that provide multi-resistance to β-lactam antibiotics such as penicillins, cephamycins, and carbapenems (ertapenem),” [wikipedia]