Another Lab Report to check microbiome: Synlab

Lab is based in Germany but available in other countries (Hungary – $140 according to reader). He gave a nice detailed summary and permission to post, so I quoted it below.

Patient Summary

“26 years old male, lives in Hungary.

Symptoms currently

-High anti-tpo levels(Hashimoto’s disease, autoimmune), level even became more elevated since I tried some probiotics.

-Sleep problems(easy to fall in sleep, but wake up after 3-4 hours and could not fall in sleep again, seems like it is constantly improving since I started to take big dose homemade chocholate (coconut oil+cacao), nettle leaf tea made from fresh leafs, and changed bed since I got to know I have dust mite allergies.

-Blurred vision, brain fog.

-Anxiety, agoraphobia, these improved since I’m under chiropractic care, I found out I had my C1 vertebra out of place, maybe since childhood.

-Sore muscles, often feel like I was doing workout.

-I’m able to do exercises, but next days I will be very fatigued.

-General low energy, but able to live my life, not locked to bed. I would say I have around 50%-60%  energy level, but become fatigued fast.

-Constant craving for chocholate.

-High blood folic acid level, this showed in my newer blood tests, after I started to experiment with different probiotics. Kinda low b12 levels, even my diet b12 rich.

-Coated tongue, especially after fruits.

-Muscle twitches.

-Chest tightness, sometimes breath difficulties.

-Rarely skin rash, dry eyes, but nothing serious.

-Not painful bloating after meals.

-No constipation, or diarrhea.

-Headaches, with not so terrible photophobia.

-Low blood pressure

-Tinnitus

Probiotics I tried:

Bio Kult, Protexin, even made yoghurt with these. At first they kinda worked, they boosted my mood,energy, but in longterm feel like they hurted slowly especially since they grown on corn, and I found out I got IgG related corn intolerance, I took them for months.

http://www.protexin.com/products/bio-kult-120-capsules/16

http://www.protexin.com/products/balance/3


-Once tried eat carrots, beets, just pulled out, and without washing few times. They worked too good, I had too much energy, but I was worried to continue eat those long enough, so I ordered Prescript-Assist, and AOR3 instead. I had zero effect from those then, but I guess I still had the bugs from raw vegetables then, but they could not make permanent changes.

-Paleo coconut yoghurt with these noname strains Bifidobacterieum lactis,Lactobacillus rhamnosus L.acidophilus,Streptococcus thermophilus, Lactobacillus reuteri(they buy reuteri from Korea, but did not tell me exact strain name), L.casei, L.bulgaricus. At first had similar effect as with Bio Gaia, but not lasted long.

-Bio Gaia L. reuteri ATCC PTA 6475,L. reuteri DSM 17938 . My brain liked these, at first gave me very calmed effect, but maybe it was just placebo, as I felt short time effect only.

-Made yoghurt with these strains and goat milk: Lactobacillus delbrueckii subsp. bulgaricus, Streptococcus salivarius  subsp. thermophilus, Lactobacillus acidophilus LA-5®, Lactobacillus  reuteri, Lactobacillus rhamnosus GG, Bifidobacterium animalis subsp.  lactis BB-12®; 0,9%). No effect.

-Goat milk kefir, homemade with these: Debaryomyces hansenii, Kluyveromyces marxianus subsp. marxianus, Lactococcus lactis subsp. cremoris, Lactococcus lactis subsp. lactis, Lactococcus lactis subsp. lactis biovar diacetylactis, Leuconostoc, Streptococcus thermophilus. My tongue did not like it, kinda burned, but I got IgG intolerance to some yeast strains.

Enterol(s. boulardii): It helped to calm down autoimmune flareup that I got from tea, but did not take long term.

Other interesting observations:

-I tried make tea with turmeric, cinnamon, black pepper, ginger. Gave me horrible autoimmune flareup, thought I will die.

-Months later I made golden paste(turmeric+coconut oil). Same effect as with tea, so I stopped instead after two days, and ordered the microbiome test to know what may happen in my gut.

-Read about chocholate’s effect on microbiome on your blog, taking high dose since few days, early to tell the experience, but so far feels promising. I will email you the result in 3 weeks.

Feel free to post my case.”

Test Results

The first part is shown below — I highlighted those that are out of range.

The rest of the report is advice. An example is below

Bottom Line

The Synlab report provides the essential information for confirm a CFS/SIBO/FM microbiome dysfunction pattern. Unlike uBiome, we do not get a detail breakdown at the genus level which would allow custom tuning of diet and supplements (to the degree that we have knowledge – which is very very limited for some bacteria genus). On the plus side, you likely get the results back much sooner (days instead of weeks).

Patient Suggestions

I am pleased to see that many things helped at least temporarily, and thank you for detailing them!

Eating unwashed out of the ground (from known clean environments) is definite a thumbs up from me. The germs on those are more likely good germs. I recall reading that the human biome is closest to ‘underground plant bacteria world’ which likely reflect our ancestral eating habits.

Turmeric(Curcumin) Response

Bactericidal Activity of Curcumin I Is Associated with Damaging of Bacterial Membrane [2015]

states “Our study shows the strong antibacterial potential of curcumin I against all the tested bacteria from Gram-positive(Staphylococcus aureus and Enterococcus faecalis) as well as Gram-negative groups(Escherichia coliand Pseudomonas aeruginosa). ”

  • “It is effective against microbial pathogens like bacteria, virus and fungi.” [2017]

My take is that turmeric is very effective against your pathogens and those are likely dumping massive quantity of toxins. You may wish to retry again starting with very very low dosages and working up. You may wish to review literature on turmeric also.

It worked once and then stopped working

There are two concepts to keep in mind:

  • Corrective — makes things better
  • Prophylactic — keeps things better

When something appears to stop working — but did work for a while, you should move it to your prophylactic list to cycle thru every few weeks originally (every few months eventually). If a prophylactic has a corrective response, you should reduce the cycle time for it.

Many CFSers want the correctiva impact, but do not get prophylactic supplements!

Where to go from here

Suggestions for going forward:

  • Theoretical Supplements at least, it allows a normal healthy microbiome to have food while we get the rest of them established.
  • Licorice may help with the low blood pressure (other readers reported success with this)
  • Discuss with your MD about systematically rotating thru every tetracycline class antibiotics available (I believe different brands of each antibiotics are likely different marginally — so on the 2nd pass, try to get a different brand when practical). See this post for why.
  • Headaches/brain fog: try regular aspirin (325mg/each meal) for a few days and also piracetam. One cause of headaches can be low oxygen delivery to tissue (common in FM). If these help, see this post and attempt to get testing for genetic coagulation defects (so you know what to treat specifically).

As always, consult with a knowledgeable medical professional before any changes of supplements etc.