Impacting Rheumatoid Arthritis bacteria genus

This is a theoretical post. Working from high bacteria and low bacteria cited in this earlier post, I went to DataPunk.Net and extracted information about each genus.

I have struck thru items that appear on both sides. We do not know if these items will help or make things worst…. i.e. these are should avoid for safety items.

The Increase or Decrease are what you in theory would reduce high bacteria and enhance low bacteria. In some cases, the same item will decrease the high bacteria and increase the low bacteria; in general, we have limited knowledge from published articles.

High Bacteria Low Bacteria
  1. Actinobacteria (phylum) 
  2. Bilophila (genus) 
  3. Clostridium asparagiforme (species) 
  4. Collinsella (genus) 
  5. Eggerthella (genus) 
  6. Faecalibacterium (genus) 
  7. Lactobacillus salivarius (species) 
  8. Oscillibacter (genus) 
  9. Parvimonas (genus) 
  10. Porphyromonas gingivalis (species) 
  11. Prevotella copri (species) 
  12. Pseudonocardia (genus) 
  13. Ruminococcaceae (family) 
  14. Veillonellaceae (family) 
    1. Agathobacter rectalis (species) 
    2. Bacteroides fragilis (species) 
    3.  Blautia coccoides (species) 
    4. Clostridiaceae (family) 
    5. Haemophilus (genus) 
    6. Peptostreptococcaceae (family) 
    7. Prevotella histicola (species)  ****
    8. Veillonella (genus) 
To Improve
Decrease Intake of
To Improve
Increase Intake of
  • Almonds/ almond skins H7
  • Arabinogalactan  H6
  • Barley  H2
  • Berberine H6 H11 H13
  • Bile  H2
  • Biotin H1
  • Chemotherapy L8
  • Chicory  H6
  • Cinnamon bark oil  L5
  • Coriander oil L5
  • Cranberry bean flour L6 H11
  • Daesiho-tang (DSHT) H7
  • Dopamine H6
  • Epinephrine H6 H11
  • Fasting H6
  • Flaxseed H11
  • Heme H11
  • High animal protein diet L1 H2
  • High carbohydrate diet H11
  • High fat diet L6
  • High fiber diet H6
  • High meat diet  H2
  • High protein diet  H2
  • High sugar diet L6
  • Inulin H6
  • Jerusalem artichoke  H6
  • Laminaria digitata (oarweed) H7
  • Lavender (spike) oil  L5
  • L-citrulline H11
  • Lemongrass oil  L5
  • Low animal protein diet  H6
  • Low carbohydrate diet L1
  • Low FODMAP diet H1
  • Low processed foods diet  H6
  • Magnesium H7
  • Mediterranean diet  H11
  • Milk-derived saturated fat  H2
  • Navy bean (Cooked)  H7
  • Partial Sleep Deprivation H4
  • Peppermint oil  L5
  • Perilla oil  L5
  • Polymannuronic acid L2 H1
  • Proton-pump inhibitors (PPI) H7
  • Pyruvate  H2
  • Red wine H6 H11
  • Resistant starch (type I)  H8
  • Resistant starch (type II) H8
  • Resistant starch (type III) H6 H8
  • Resveratrol H7
  • Saccharin H13
  • Saccharomyces boulardii H6 H11 H13
  • Sesame cake/meal H7
  • Sucralose (Splenda) L2
  • Thyme oil L5
  • Walnuts H6 H13 L2 L3
  • Whole grain diet H4
  • Whole-grain barley L2
  • β-Glucan L2
  • (+)-Catechin H11
  • Bile salts  H6
  • Chemotherapy H5 H6 H7
  • Chicory H2 H11
  • Dopamine H11
  • Epicatechin H11
  • Flaxseed  H6
  • Fructo-oligosaccharides L2 H6
  • Gallate H6 H13
  • Gallic acid L2
  • Glyphosphate H7
  • Grapes (table) H2
  • High animal fat diet  H6
  • High animal protein diet  H6
  • High fat diet H6 H7 H13
  • High meat diet L2
  • High processed foods diet  H6
  • High sugar diet H6 H13
  • Inulin H2 H11
  • Jerusalem artichoke H11
  • Laminaria hyperborea (curvie) H7
  • L-citrulline L2
  • Low carbohydrate diet H11
  • Low fat diets L2
  • Low fiber diet  H6
  • Low FODMAP diet  H6
  • Magnesium-deficient diet H7
  • Navy bean (Cooked) H4 H6 H11
  • Omega 3 fatty acids  H6
  • Proton-pump inhibitors L5 L8
  • Red wine L1 L2
  • Resistant starch (type IV) L2 H6 H11
  • Resveratrol H11
  • Saccharin L2 L4 L6
  • Stevia L2 H7
  • Stigmastanol H4
  • Sucralose (Splenda) H7
  • Tannic acid L2
  • Whole-grain barley H11
  • β-Glucan H11
  • β-sitosterol H4

For caution, we should ignore items that impact only one of the bacteria. We want items that impact several bacteria.

Bottom Line

Some of the increased items above appears to be backed by the literature:

There were some pleasant surprises above…

  • On the right there are a lot of sugar substitutes (Saccharin, Stevia, Sucralose / Splenda)…. and evidence is that they reduce risk of RA! They may also reduce the severity (speculation)
    • “Regular consumption of sugar-sweetened soda, but not diet soda, is associated with increased risk of seropositive RA in women, independent of other dietary and lifestyle factors.” [2014]
  • Resistant starch Types I,II,III are all should be reduced while Type IV should be increased.
      • “Dietary modulation of the gut microbiota impacts human health. Here we investigated the hitherto unknown effects of resistant starch type 4 (RS4) enriched diet on gut microbiota composition and short-chain fatty acid (SCFA) concentrations in parallel with host immunometabolic functions in twenty individuals with signs of metabolic syndrome (MetS). Cholesterols, fasting glucose, glycosylated haemoglobin, and proinflammatory markers in the blood as well as waist circumference and % body fat were lower post intervention in the RS4 group compared with the control group. 16S-rRNA gene sequencing revealed a differential abundance of 71 bacterial operational taxonomic units, including the enrichment of three Bacteroides species and one each of ParabacteroidesOscillospiraBlautiaRuminococcus, Eubacterium, and Christensenella species in the RS4 group. Gas chromatography–mass spectrometry revealed higher faecal SCFAs, including butyrate, propionate, valerate, isovalerate, and hexanoate after RS4-intake. “[2016]
        • This was a human study and used 30% RS4 enriched flour.
        • One source.

For magnesium (where for CFS/FM in general, more is better) we have the opposite being suggested above, that is reduce it!!. Looking at studies — a reduced level appear to help RA.

This is the second time that we observed: microbiome shift seen in an autoimmune condition–> what corrects the shift –> studies confirm the suggestions improves the condition.

As always consult with your medical professional before changing diet or supplements. The above considers the condition is isolation of other conditions that may be a factor.