Italian State of the Art Microbiome Report #2 Male

A reader forwarded me two reports, one from a male and one from a female. No notes on the people (I am fine with that). The report appear to be superior to uBiome on two counts:

  • It’s a professional grade report from a clinical laboratory
  • It reports down to the strain level on occasion.

This second post is on the male. (See this post for the female)

  • Low Bifidobacteria
  • No Lactobacillus
  • No E. coli
  • Low Akkermansia muciniphila (less than 1/100 of 1% of typical)

So standard CFS profile on these


Copying the data to Excel allow me to get similar numbers as I do from uBiome reports.

High Levels

We have a lot more with the male than the female.

Proteobacteria  Haemophilus parainfluenzae 9911% 0.00892
Bacteroidetes Bacteroides ovatus 8200% 0.00574
Proteobacteria  Klebsiella 3000% 0.0003
Firmicutes  Roseburia faecis 1700% 0.00017
Bacteroidetes Bacteroides uniformis 1526% 0.13722
Firmicutes Blautia 1342% 0.24124
Firmicutes  Roseburia 878% 0.04691
Firmicutes  Ruminococcus gnavus 775% 0.01783
Firmicutes  Epulopiscium 720% 0.00036
Firmicutes  Anaerostipes 717% 0.01993
Firmicutes  Lachnospira 561% 0.00185
Firmicutes  Dorea 440% 0.03024
Firmicutes  Bulleidia 361% 0.00231
Firmicutes  Clostridium 341% 0.00133
Firmicutes  Ruminococcus 333% 0.11271
Firmicutes  Oscillospira 271% 0.02044
Actinobacteria Eggerthella lenta 257% 0.00399

The greatest impact (volume of metalites produced) appears to be (in order) from  Blautia, Bacteroides uniformis , Ruminococcus, Roseburia.  I have done just the 8 highest below (for the moment — I may return to expand more in the future).


Bottom Line

Combining all of the lists and tossing out things that appear on both side, we have the following lists. There are two genus cited above that I have not done a deep dive into. I have skipped rare bacteria because of the number of over growths found. This was a pretty clean merge — often the same item appeared multiple times in one list or the other.

The lists below are done by merging the lists from the deep dives linked above. Some items may encourage one genus and discourage another genus — those are removed (unless it seems that it strongly predominates on one). The impact on Lactobacillus, Bifidobacterium and E.Coli are intentionally ignored [See this post for the logic]. This is all based on applying logic to the results of studies — thus theoretical. This is an addition (not a replacement) to this overview post.


  • Animal-based diet
  • Arabinoxylans
  • Arginine supplements
  • Bacillus probiotics
  • Berberine.
  • Bifidobacterium adolescentis
  • Bifidobacterium Animalis  subsp lactis BB-12
  • Broad beans  and lupin seeds
  • Brown rice
  • Butyrate producing probiotics
  • Chili pepers
  • Cholic acid
  • Dietary fiber
  • Dopamine
  • Favone
  • Fluoroquinolone
  • Fructo-oligosaccharides
  • Gallic acid
  • Glucose foods (fructose [fruit sugar] appears to be fine)
  • Gum arabic
  • Gynostemma pentaphyllum
  • Helminth infections
  • High grain diet
  • Inulin
  • Lactobacillus acidophilus
  • Lactobacillus fermentum
  • Lactobacillus plantarum
  • L-citrulline
  • Metformin
  • N-Acetyl-D-glucosamine
  • Omega 3
  • Polydextrose
  • Polymannuronic acid
  • Resistant maltodextrin.
  • Rosemary
  • Saccharin
  • Saccharomyces boulardii
  • Safflower oil
  • Salt
  • Sodium butyrate
  • Soy
  • Stevia
  • Stress
  • Tannic acid


  • Bifidobacterium longum BB536
  • Bile acid
  • Epinephrine
  • Flaxseed
  • Fructo-oligosaccharides
  • Galactooligosaccharides
  • Garlic
  • Lactobacillus paracasei (24 billion viable /daily)
  • Lactobacillus casei strain Shirota (Yakult brand)
  • Lactobacillus kefiri LKF01 
  • l-glutamine
  • Low carbohydrate diet
  • Mutaflor (E.Coli Nissle 1917)
  • Oral Iron Supplements
  • Oranges (pectin/flavanones)
  • Polymannuronic acid
  • Proton-pump inhibitors (PPI)
  • Streptococcus probiotics
  • Sucralose (Splenda)
  • Tea Tree Oil
  • Vitamin D3


This is an education post to facilitate discussing this approach with your medical professionals. It is not medical advice for the treatment of CFS. Always consult with your medical professional before doing any  changes of diet, supplements or activity. Some items cites may interfere with prescription medicines.