The reader whose uBiome I reviewed here in September, did a followup with his FMT donor and got permissions from the healthy donor to share. This is of great interest because FMT for CFS tend to work well for a while and then the patient relapse. Understanding the factors involve with FMT is an important quest.
- Lactobacillus: 0x
- Bifidobacterium: 4.07x
- Akkermansia: 0x
- Diversity: 59%ile
- Firmicutes to Bacteroidetes: 1.8:1 (Normal 2.1:1)
|Bacteria name||Rank||% of Samples|
It is interesting to note that every high genus (apart from Bifidobacterium) is on the list of typical overgrowths seen with CFS (see this post)
In my earlier post, Theortical Protocol for Fecal Transplants for CFS/IBS etc, I suggested “donor should not have any bacteria genus > 1.5x that the recipient has > 1.5x.” This donor match this criteria, so well it may be helpful (as it was in this case), I would like to suggest raising the threshold to: “No bacteria genus > 1.5x should be on the list of common bacteria genus overgrowths listed at Overview of this Blog and the Microbiome.“
How can the donor be healthy with no Lactobacillus?
There are several possible answers:
- He may be taking adequate supplements to compensate.
- His DNA (remember DNA SNPs are associated with CFS/IBS/FM and symptoms).
- Other bacteria may be compensating
- He may be borderline CFS
- The high Bifidobacterium compensated.
This is an education post to facilitate discussing this approach with your medical professionals. It is not medical advice for the treatment of any condition. Always consult with your medical professional before doing any changes of diet, supplements or activity. Some items cites may interfere with prescription medicines.