Revisiting obesity and leanness

We are aware that microbiome influence obesity, with charts like the one below [2015] [2017]

pone.0134333.g001

Gut-microbiota-composition-in-normal-weight-and-obese-children-The-innermost-ring-shows

This last week a lovely study was published:

Citrus peel extracts attenuated obesity and modulated gut microbiota in mice with high-fat diet-induced obesity.[ June 1, 2018] which stated “Compared to the case of the HFD group, PMF B altered the gut microbiota by increasing Prevotella and decreasing rc4-4 bacteria.”

rc4-4 means a genus under Firmicutes; Clostridia; Clostridiales; Peptococcaceae; rc4-4;

Related under the Peptococcaceae family are:

As you can see, there are some 13% of this family that do not have a reported genus in uBiome results.

More on Citrus Peels

So, it appears eating the peel of citrus fruit may have significant impact on obesity.

More on Prevotella

Bottom Line

Some people with various conditions will lose weight for years and then suddenly increase weight with the same, or even greatly reduced calories/diet.  The simple explanation is that their microbiome has shifted.  Correcting the shift by adding citrus peel to meals as a filler may both help with the weight issue and may even help with other health conditions.