Why you react to some probiotics – some answers

A reader wrote today:

“I have been trying B. longum BB536 as I have read it lowers d lactate producers

Seems its helping gut function but giving hot flashes and some heart palps, wondering why?”

The light went on — I have just gotten a reasonable size of end-products relationships (5800). Perhaps we may be lucky and get some idea of what B.longum does.

So I have added end products to the bacteria detail pages. For example:

http://microbiomeprescription.azurewebsites.net/Library/Details?taxon=216816&taxname=Bifidobacterium%20longum

And you will see at the bottom of the page:

End Products

  • ?-Amino butyric acid (GABA)
  • Biotin (Vitamin B7)
  • Folate (Vitamin B9)
  • Lactic acid
  • L-Tryptophan
  • Pyridoxine
  • Thiamine (Vitamin B1)
  • Urolithins

If I go to another probiotic, Lactobacillus acidophilus,  I see a different combination,

End Products

  • ?-Amino butyric acid (GABA)
  • Acetylcholine
  • Cobalamin (Vitamin B12)
  • Lactate
  • Lactic acid
  • Trimethylamine
  • Urolithins
  • Vitamin K

Or looking at my favorite Japanese probiotic,  Miyarisan (Clostridium butyricum)  we see here

End Products

  • Acetate
  • Butanol
  • Butyrate

And another Japanese one, Lactobacillus Casei

End Products

  • ?-Amino butyric acid (GABA)
  • Acetylcholine
  • Cobalamin (Vitamin B12)
  • Histamine
  • Lactate
  • Lactic acid
  • ß-Glucan
  • Trimethylamine
  • Urolithins

Bottom Line

This presents a very different way of looking at probiotics. If you have a low amount of an end product (or symptoms associated with a low amount), then you may wish to surf thru the probiotics listed (with other bacteria) here.

For more information on EndProduct determination from a uBiome or Thryve sample, see: