Patents and ME/CFS

A reader forwarded me a copy of a 2019 patent application Therapeutic agent for chronic fatigue syndrome. Patents are an interesting mining source because often they come from unpublished studies. The last time that I did a patent review, I found some interesting stuff.

On the flip side, the inclusion of ME/CFS in the patent application rarely means that the focus is ME/CFS. Patents are written to be ascribe every possible use just in case someone later discover a use. I have several patents and have written over a half dozen of them.

This is a quick review of a few of the more interesting patent applications that mentions ME/CFS:

Bottom Line

Only one was CFS specific, Japanese horseradish (wasabi) . There were many dealing with FMT — I enjoyed seeing the “Fecal Floral Transplant” – A shit by any other name (to paraphrase Shakespeare)

Looking at wasabi or horseradish, I found no significant literature on it’s impact on the microbiome. I found just 140+ studies citing wasabi

Since the western diet is relatively devoid of deeply-colored fruits, vegetables and other plant-derived culinary items (e.g., turmeric, ginger, seaweeds, purslane, wasabi, Brassica-family sprouts, and regional spices) this represents a loss of complex phytochemicals that would otherwise make their way into the gastrointestinal tract

The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases [2016]

Wasabi does appear to have significant benefit for a variety of stomach ailments. It is likely beneficial for many digestive issues — NOTE: that it may be harmful for people with the FOXO3 mutation (we are back to the DNA-Microbiome interaction complexities).