Vasodilation means opening up or dilatation of blood vessels, which will often decreases blood pressure. I put together a list of supplements (with links to PubMed studies) that reduces blood pressure in a September 2019 post. An item that reduces blood pressure does not always mean that it does vasodilation. Some migraines and headaches are improved by vasodilation

In this post I will review these and other supplements that dilation of blood pressures.

• Niacin (Vitamin B3) — my long time favorite. Does nicotinic acid (niacin) lower blood pressure? [2009]
• Magnesium — Mechanisms of magnesium-induced vasodilation in cerebral penetrating arterioles [2016]
• PUFA – Polyunsaturated Fatty Acids (PUFA) Are Cerebral Vasodilators via the TREK-1 Potassium Channel [2007]
• l-Arginine – l-Arginine Induces Nitric Oxide–Dependent Vasodilation in Patients With Critical Limb Ischemia [1996]
• Vitamin C – Vitamin C Improves Endothelium-Dependent Vasodilation in Forearm Resistance Vessels of Humans With Hypercholesterolemia [1997]
• Resveratrol — Evidence for Circulatory Benefits of Resveratrol in Humans [2013]
• coenzyme Q10 —Effects of coenzyme Q10 supplementation (300 mg/day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy: a randomized, placebo-controlled trial [2013]
• Melatonin —Melatonin Mediates Vasodilation Through Both Direct and Indirect Activation of BK _Ca Channels [2017]
• Lycopene — Lycopene and Vascular Health [2018]
• Taurine — Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension [2016]
• Piracetam – Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic [2016]
• Potassium — Role of Potassium in Regulating Blood Flow and Blood Pressure [2006]

And so on, almost every item that reduces blood pressure also induces vasodilation (not really much of a surprise).

Complex Interactions

• Calcium “The influx of calcium into vascular smooth muscle initiates contraction by binding to” [1983]