A reader asked if Streptococcus was known to be associated with any psychiatric disorders.  My immediate response is YES, Dr Philippe Bottero had an reported remission rate of over 75% in treating patients at a psychiatric hospital with antibiotics back in the late 1990’s.  His success with a non-conventional approach resulted in his ability to practise being severely restricted by the establishment (according to private information) – Report is here on treatment.

Jump ahead a few decades and what do we find on PubMed?

• Detection of anti-streptococcal, antienolase, and anti-neural antibodies in subjects with early-onsetpsychiatric disorders.[2015]
  • • “Infection with group A Streptococcus (StrepA) can cause post-infectious sequelae, including a spectrum of childhood-onset obsessive-compulsive (OCD) and tic disorders with autoimmune origin (PANDAS, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections)…The simultaneous detection of all three of these antibodies could provide valuable information for the etiologic diagnosis of individuals with early-onset obsessive-compulsive disorders associated with streptococcal infection and, consequently, for prescribing suitable therapy.

   

•  Streptococcal upper respiratory tract infections and exacerbations of tic and obsessive-compulsive symptoms: a prospective longitudinal study. [2011]
• Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and tics. [2004]
• Neurocognitive functioning in youth with pediatric autoimmune neuropsychiatric disorders associated with streptococcus. [2011]
• Pediatric autoimmune neuropsychiatric disorders associated with Streptococcus in identical siblings. [2011]
• Association between streptococcal infection and obsessive-compulsive disorder, Tourette’s syndrome, and tic disorder. [2005]

And for other bacteria:

• Psychiatric symptoms in patients with Shiga toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome.[2014]
• Clinical and neuropsychological characteristics of general paresis misdiagnosed as primarypsychiatric disease. [2016] – “Our findings reinforce the importance of performing serologic testing for syphilis. This should be a part of the evaluation of patients with psychiatric disorders, especially patients with cognitive impairment. “
• Bacterial neuroactive compounds produced by psychobiotics.[2014]
• [A psychiatric disorder reveals a neurobrucellosis]. 2016
• Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder. [2016] “Our results provide direct evidence, for the first time, that individuals with lower Bifidobacterium and/or Lactobacillus counts are more common in patients with major depressive disorder compared to controls.”

Bottom Line

The presence or absence of some bacteria can cause psychiatric effects. This is not restricted to Streptococcus.

A reader ask this question “If I have no lactobacillus, and most lactobacillus probiotics are not human source (so will not stay around), is there any hope to recover lactobacillus?”.  Looking at the data I found on 343 samples only 15 samples has no measurable lactobacillus. If the number is very low, ubiome will report it as none.

Those with subsequent ubiomes with lactobacillus.

Some Examples:

• AC:
  • Original: null
  • 2014: 772
  • 2015 1819
• AK
  • 2017-08: null
  • 2017-12: 52
• TK
  • 2016-02: null
  • 2017-01: 936
  • 2017-03: 108
  • 2017-09: 1996

One reader had them wrapped out, I assume due to antibiotics or other prescription drugs.

• 2018-03: 128092
• 2018-05: null

Bottom Line

There appears to be evidence that Lactobacillus will repopulate over time.

I have an extensive list of drugs with their impact on  http://microbiomeprescription.com/Library/GutModifiers.

The question arose in one of my facebook groups — what should I do when I am taking this or that antibiotics.

Conceptually, it is simple —

• Lookup that antibiotic
• See which bacteria it modifies
• See what you can take to counteract it’s effect.

The problem is that for some items, the data volume explodes!

I have added a new link and a new page. When you click on a modifier that is an antibiotic,  for example, http://microbiomeprescription.com/Library/Modifier?mid2=534,

You will see a new link on some of them

Clicking on that, takes you to the suggestions to minimize the antibiotic impact on the microbiome.

More important, at the bottom are things you may wish to give up while on the antibiotic.

Bottom Line

I attempted to keep prescription items off the list, but data still has a lot of cleanup waiting. For example, two antibiotics snucked into the avoid list.

I believe this is the first time, anyone has given science/studies based recommendations on what to do when taking antibiotics. Most of the usual advice has been folk-lore and hearsay. We now have some science.

This is an education post to facilitate discussing this approach with your medical professionals. It is not medical advice for the treatment of any medical condition. Always consult with your medical professional before doing any  changes of diet, supplements or activity. Some items cites may interfere with prescription medicines.

There is a comparison tool at http://microbiomeprescription.com/ which allows you to view change in three different ways:

• Change in number of matches to known illness profiles
• Change in End Products product
• Counts of Bacteria.

How to do it

On the landing page after logging in you will see this at the top. Click it.

You will then be presented with available samples

Select at least two. then click one or another of the three buttons.

Summary — Compare to Profiles

In general, you want your numbers to go DOWN, especially if you have a listed condition

EndProducts – Metabolites produced by the bacteria

Details – by Bacteria, Symptoms, Metabolism

There are three reports here — two may be empty if you did not enter information. The last one is always there: Bacteria Change

Bottom Line

The two easiest to interpret on the first ones:

• How many shifts are matches with known shift in different illnesses
• Are you moving closer to the end products seen in healthy people

From: https://www.fda.gov/safety/recalls/ucm612266.htm