Category Archives: Conditions

Unknown's avatar lassesen 4:53 am on November 1, 2017  

Reducing Succinivibrio genus

For updated information see Microbiome Prescription

DataPunk.Net Data

No Information

PubMed Data

There are 60+ studies on PubMed

Disease

Diet

  • “Thiamine supplementation increased the abundance of cellulolytic bacteria including Bacteroides, Ruminococcus 1, Pyramidobacter, Succinivibrio, and Ruminobacter” [2017]
  • “Succinivibrio and Halomonas from the Proteobacteria phylum were overrepresented in omnivores. (vs vegetarians) [2017]
  • ” The levels of Selenomonas ruminantium, Anaerovibrio lipolytica, Ruminobacter amylophilus, Succinivibrio dextrinosolvens and Megasphaera elsdenii were increased by ginkgo extract supplementation, ” [2017]
  • ” Perilla frutescens seed extract was accompanied by an increased abundance of Ruminobacter, Selenomonas, Succinivibrio, Shuttleworthis, Pseudobutyrivbrio, Anaerovibrio, and Roseomonas and a decreased abundance of Methanobrevibacter millerae.” [2016] –  Korean perilla, is a species of Perilla in the mint family Lamiaceae.
  • “Adding sodium bicarbonate also decreased (P < 0.05) the relative abundance of Streptococcus and Butyrivibrio and increased (P < 0.05) the proportions of Ruminococcus, Succinivibrio and Prevotella.” [2017]

Prebiotics

Probiotics

  • “Interestingly, B. lactis supplementation slightly reduced the abundance of the genera Ruminococcus (from the Ruminococcaceae family) and Succinivibrio compared to the standard formula group ” [2016]

Antibiotics

  • “the genus Succinivibrio were decreased in the pigs fed… chlortetracycline” [2017]

Bottom Line

Avoid

  • Thiamine
  • Ginkgo
  • Sodium bicarbonate

Take

  • Reduce meat consumption
  • Bifidobacterium animalis subsp. lactis (slight impact)
Unknown's avatar lassesen 4:18 am on November 1, 2017  

Reducing Acidaminococcus genus

The Acidaminococcus genus was created in 1969 and actually counts as two species with standing in nomenclature: A. fermentans and A. intestini. Cells belonging to this genus are Gram-negative, anaerobic cocci, generally isolated from the digestive tract of mammals [5], [6]. [2017]

For updated information see Microbiome Prescription

DataPunk.Net Data

Nothing

PubMed Data

There are 110+  studies on PubMed

Disease

  • Rosacea ” reduced abundance of Peptococcaceae family unknown genus, Methanobrevibacter (genus), Slackia (genus), Coprobacillus (genus), Citrobacter (genus), and Desulfovibrio (genus), and increased abundance of Acidaminococcus(genus), Megasphaera (genus),” [2017]
  • ” type 1 diabetes mellitus … the composition of Haemophilus, Lachnospira, Dialister, and Acidaminococcus was decreased.” [2016]

Diet

  • “Acidaminococcus, Bifidobacterium, Megasphaera and Mitsuokella were greater (P< 0·05) in moderate-protein, moderate-carbohydrate-fed kittens. (compared to High-protein, low-carbohydrate ) [2013]
  • “that glutamate is fermented … via the hydroxyglutarate pathway by Acidaminococcus fermentans” [1974]

Prebiotics

Probiotics

  • ” Bacillus natto and Lactobacillus acidophilus …Haemophilus decreased, Ruminococcus decreased, Clostridium colinum decreased, Acidaminococcus increased and Megamonas increased individually.” [2008]

Antibiotics

  • “Fosfomycin ..14% of Acidaminococcus fermentans strains were resistant. no Acidaminococcus fermentans strains showed resistance to the (penicillin G) antibiotic at this concentration.” [1992]

Bottom Line

Avoid

  • Bacillus natto (likely all bacillus)
  • Lactobacillus acidophilus
  • Glutamate

Take

  • High-protein, low-carbohydrate diet
Unknown's avatar lassesen 2:45 am on November 1, 2017  

Review of Biohm Probiotics

A reader asked me about this probiotic sold at https://biohmhealth.com.

“BIOHM contains B. breve, L. acidophilus, L. rhamnosus, S. boulardii and Amylase”

It appears to be directed at fungal infection.

Is it good for CFS?

Well, S. boulardii encourages the growth of many bacteria genus  seen in CFS that are already overgrown!!

“Saccharomyces boulardii is a tropical strain of yeast first isolated from lychee and mangosteen fruit in 1923 by French scientist Henri Boulard.” DataPunk.Net

A few examples:

For Lactobacillus acidophilus, the same issue

Bottom Line

Unless your microbiota shifts happen to land between all of the above bacteria genus, this probiotics is likely more harmful than good for CFS patients. It is high risk without a microbiome analysis to determine suitability first.

 

 

Unknown's avatar lassesen 3:25 am on October 31, 2017  

A CFS Patient since a child – Ubiome Analysis

The short form of the patient history is ” I’m very sick from CFS and MCS and Lyme, I’ve been sick since I was 11 years old, now I’m 34 years old.”

Standard Items

  • Bifidobacterium < 0.01
  • Lactobacillus 0.07x
  • Akkermansia: 0.00x
  • Firmicutes to Bacteroidetes: 1:2, Normal is 2.1:1
  • Biodiversity: 41%ile — much lower than most.

High Bacteria

Bacteria

Ratio
Sutterella: 11.02 X
Barnesiella: 4.16 X
Pseudobutyrivibrio: 3.11 X
Odoribacter: 2.91 X
Butyricimonas: 2.18 X
Kluyvera: 1.91 X
Bacteroides: 1.64 X

Rare Bacteria

Johnsonella Genus 0.5%
Ureaplasma Genus 0.8%
Mycoplasmataceae Family 1.3%
Mycoplasmatales Order 1.3%
Brevundimonas Genus 2.0%
Caulobacteraceae Family 3.0%
Caulobacterales Order 3.0%
Anaerobacter Genus 3.0%
Succiniclasticum Genus 4.0%
Candidatus Saccharibacteria Phylum 4.2%

Bottom Line

Combining all of the lists and tossing out things that appear on both side, we have the following lists. I have skipped rare bacteria because of the number of over growths found. This was a pretty clean merge — often the same item appeared multiple times in one list or the other.

The lists below are done by merging the lists from the deep dives linked above. Some items may encourage one genus and discourage another genus — those are removed (unless it seems that it strongly predominates on one). The impact on Lactobacillus, Bifidobacterium and E.Coli are intentionally ignored [See this post for the logic]. This is all based on applying logic to the results of studies — thus theoretical. This is an addition (not a replacement) to this overview post.

Working off the overgrowth only (I will revisit the rare bacteria when I have more time). It was interesting that some of the probiotics appeared multiple times for different genus as Avoid or Take — which left me a warm feeling. Two of the “fake sugars” are bad (Aspartame (Nutrasweet) and Stevia) and two are good (Sucralose (Splenda) and Xylitol)

Avoid

Take

This is an education post to facilitate discussing this approach with your medical professionals. It is not medical advice for the treatment of CFS. Always consult with your medical professional before doing any changes of diet, supplements or activity. Some items cites may interfere with prescription medicines.

Unknown's avatar lassesen 3:02 am on October 31, 2017  

Reducing Kluyvera Genus

This genus is always associated with disease. It is usually subject to aggressive antibiotic treatment.  It appears to be present is some 20-30% of CFS patient’s uBiome seen so far.

For updated information see Microbiome Prescription

DataPunk.Net Data

“Enterobacteriaceae like Kluyvera are not very friendly and tend to thrive in the inflamed gut. ”

INHIBITED BY

ENHANCED BY

ANTIBIOTIC RESISTANCE

PubMed Data

There are 230+ studies on PubMed — this is just from a select sampling.

Disease

Diet

  • Ineffectual: Lemongrass, Artemesia vulgaris  (wormwood), Nutmeg oil, Selinum wallichianum Essential oil (or) Milk Parsley [2015]
  • study which shows that oil of Mexican oregano works against kluyvera cryocrescens. the active ingredient of Mexican oregano and common oregano are the same, carvacrol. From a reader, Study

Prebiotics

Probiotics

Antibiotics

  • “. Successful treatment options include third-generation cephalosporins, aminoglycosides, betalactams with beta-lactamase inhibitors and carbapenems. ” [2015]
  • “In contrast, the resistance to ampicillin, extended-spectrum penicillins, and first- and second-generation cephalosporins is significant. Kluyvera is a potentially virulent pathogen that deserves aggressive treatment designed with an awareness of the organism’s antimicrobial resistance patterns.” [2001]

Bottom Line

This is a tough genus to reduce without using antibiotics. No known probiotics impacts it.

Avoid

Take