Reducing Collinsella genus

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PubMed Data

There are about 80+ articles on PubMed.

  • Disease
    • “The abundance of Collinsella correlated strongly with high levels of alpha-aminoadipic acid and asparagine as well as production of the proinflammatory cytokine IL-17A. A role for Collinsella in altering gut permeability and disease severity was confirmed in experimental arthritis.” [2016]
    • “Genus Collinsella…found to be significantly increased in type 2 diabetes compared to the other groups ” [2015]
    • “the genus Collinsella was enriched in patients with symptomatic atherosclerosis,” [2012]
    • Collinsella have been correlated or causally related to rheumatic disease.” [2016]
    • “At the genus level, we observed significant increases in the numbers of … Collinsella,… in the Food Sensitive group. ” [2016]
    • “Unaffected relatives of patients with Crohn’s Disease had less Collinsella aerofaciens ” [2011]
    • “a positive correlation was detected between serum cholesterol and Collinsella (Coriobacteriaceae). ” [2013]
    • “Collinsella aerofaciens, an abundant actinobacterium, were significantly
      decreased in all IBS subtypes compared with the Healthy Controls.” [2010]
  • Diet:
    • Collinsella decreased significantly at week 4 compared to baseline[ with pomegranate extract] . ” [2015]
    • “decreased, along with Collinsella aerofaciens, on reduced carbohydrate weight loss (WL) diet.” [2011]
    • “The the fibre-rich macrobiotic Ma-Pi 2 diet , but not the control diet, was also effective in counteracting the increase of possible pro-inflammatory groups, such as Collinsella and Streptococcus, in the gut ecosystem, ” [2016]
    • “certain bacterial groups was lower (…Collinsella ..)  among vegetarians,” [2014]
    • “bacteria related to Collinsella and members of the Clostridium clusters IV and XI increased  in the group consuming refined wheat breads. ” [2013]
    • “In addition, the genera Eggerthella, Collinsella and Corynebacterium within Actinobacteria, along with bacteria related to Bacteroides vulgatus and Prevotella oralis, were stimulated after the  non-starch polysaccharides  diet.” [2014]
  • Prebiotics:
    •  Collinsella sp., were detected in microbiota of the rats fed raffinose. [2016]
    • “The synbiotic increased relative abundances of the Collinsella, ” [2014]
  • Probiotics:
    • “Lactobacillus reuteri DSM 17938  … lower Collinsella and higher Enterococcus and Coprococcus abundance at 4 months.” [2016]
  •  Antibiotics:
    • ” Collinsella spp., and Eubacterium spp. showed variable resistance to penicillin. ” [2014]
  • “lower numbers of Collinsella spp. were evident in the elderly subjects with non-steroidal anti-inflammatory drugs (NSAID) compared both with young adults and the elderly without NSAID, suggesting that the use of NSAID along with age may also influence the composition of intestinal microbiota. ” [2010]
  • “per oral iron replacement treatment was associated with decreased abundances of operational taxonomic units assigned to the species Faecalibacterium prausnitziiRuminococcus bromiiDorea sp. and Collinsella aerofaciens.” [2017]
  • “The relative proportions of …Collinsella, … were significantly correlated with weight loss induced by tea extracts” [2017]

Bottom Line

  • Reduce refined wheat breads, switch to rye breads[2013]
  • Some oral iron supplements
  • Green or black tea
  • pomegranate (walnuts is likely helpful too)
  • NSAIDs (see list here), I prefer aspirin as first choice.