Reducing Faecalibacterium genus

Some CFS patients are low and some are high.  I have done 2 earlier posts:

This consolidates and expands with new data.

For updated information see Microbiome Prescription

DataPunk.Net Data






PubMed Data

There are 540+ articles on PubMed. Over 320 of the articles deal explicitly with Faecalibacterium prausnitzii

  • Disease:
    • “major depressive disorder … reduced levels of Faecalibacterium. ” [2015]
    • Faecalibacterium, was lower in patients with multiple sclerosis.” [2015]
    • “The relative abundance of the bacterial genera …Faecalibacterium… was significantly decreased in children at risk of asthma” [2015]
    • “Bacteria from the genus Faecalibacterium were significantly more abundant in the mucosa of controls than Parkinson’s disease”. [2015]
    • “Lower in autism” [2013]
    • “At the genus level, we observed significant increases in… Faecalibacterium, … the Food Sensitivity group.”[2016]
    • “relative abundance of … Faecalibacterium…was reduced in Sjögren syndrome compared to controls. ” [2016]
    • ” Faecalibacterium prausnitzii was sharply decreased in both the fecal and biopsy specimens of the active CD patients” [2014]
  • Diet:
    • “after 6 weeks of intervention with flaxseed mucilage showed alterations in abundance of thirty-three metagenomic species (P< 0.01), including decreased relative abundance of eight Faecalibacterium species. ” [2015]
    • “Associated growth of levan-degrading (e.g. Bacteroides) and butyric acid-producing (e.g. Faecalibacterium) taxa was observed in levan-supplemented media. ” [2015]
    • Increased gut microbiota diversity and abundance of Faecalibacterium prausnitzii and Akkermansia after fasting: a pilot study [2015].
    • The microbial groups that increased significantly from lupin seeds (Lupinus albus) and broad beans (Vicia faba)…Faecalibacterium prausnitzii [2015]
    • “All strains tested were bile sensitive, showing at least 80% growth inhibition in the presence of 0.5 μg/ml bile salts, “[2012]
    • ” Faecalibacterium prausnitzii proportions decreased (P = 0.007, P = 0.031 and P = 0.009, respectively) as a result of the gluten-free diet” [2009]
    • “was found to be significantly lower in broccoli-fed mice.” [2012]
    • “chitooligosaccharides (COS) and low molar mass chitosans (LMWC)…decreased in all strains ” [2012] [2006]
  • Probiotics:
  • Antibiotics
    • Rifaximin appeared to influence mainly potentially detrimental bacteria, such as Clostridium, but increasing the presence of some species, such as Faecalibacterium prausnitzii.” [2015]
    • Metronidazole… known to decrease anaerobes such as Faecalibacterium” [2016]
    • “The relative abundance of Faecalibacterium prausnitzii was unaffected except with thymol [Thyme Oil] at 500 p.p.m. of essential oils tested”
    • “proton pump inhibitor…was accompanied by a lower abundance of Faecalibacterium spp.” [2012]
    • “Oral Iron supplements treatment was associated with decreased abundances of operational taxonomic units assigned to the species Faecalibacterium prausnitzii,”  [2017]

Bottom Line


  • VSL#3 Probiotics
  • Bifidobacterium adolescentis  Probiotics
  • Bifidobacterium pseudocatenulatum
  • Saccharomyces boulardii
  • Enterococcus probiotics
  • Walnuts (or pomegranates)
  • Jerusalem artichoke, Inulin, Chicory
  • Berberine
  • High Fiber Diet
  • red wine (or grape seed extract or reservatol)
  • Rifaximin