Neurology – Sample Microbiome Analysis

In my last post, Dementia: Alzheimer’s Disease, I gave background on why microbiome alteration may moderate, perhaps reverse, the progression Alzheimer’s disease. In this post, I will show how you can get suggestions.

After uploading your 16S Microbiome (this can be done here), you will see displayed a link to analysis. Clicking it will take you to this page. Click any of the yellow items.

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This will then go to the suggestions page.

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Instead of trying to change everything, we focus on the bacteria associated with Alzheimer’s. This is simple. Just pick Alzheimer’s

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Probiotics

Uncheck all items under Modifier Types except probiotics. There can be information overload with suggestions. Click the button “Modify Recommendation by above choices”

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The yellow items above are items where it will make some of the bacteria better and some worst. I usually suggest avoiding all of them unless there are no other choices.

For probiotics, often they are mixtures — if all of them are on the Take list (without any yellow), then that is ideal.  For this example, if it contains any lactobacillus acidophilus then do not use it.

If you cannot find some of them, or any mixtures containing poor one,  you may wish to go to https://www.customprobiotics.com/ — this site sells single strain probiotics so you just order precisely what you. The price seems high but the actual cost per community forming units is very low. Some, like Mutaflor escherichia coli nissle 1917 (probiotics) is available in only some countries (Canada, Europe, Australia).

Vitamins

Some vitamins act as antibiotics when taken in sufficient dosage. For this sample, only vitamin D, magnesium and selenium are clear suggestions with no known negative aspects. Iron and selenium levels should be checked by your MD before starting. All of them should be at least at the average level according to the lab. For Vitamin D levels I prefer to be close to the top of the range – for older people, this may mean  15,000 IU/day to raise levels.

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Others

Explore the other choices. For the above sample, Mediterranean Diet was the strongest suggestion. Using raffinose(sugar beet)  for a sweetner.

Bottom Line

Interpret “Take” as increase or add to diet. “Avoid” as decrease or remove.  Each item should contribute — you do not need to do everything.

This is an education post to facilitate discussing this approach with your medical professionals. It is not medical advice for the treatment of any medical condition. Always consult with your medical professional before doing any  changes of diet, supplements or activity. Some items cites may interfere with prescription medicines.