This is the sparsest deep dive — if you find anything, please comment

For updated information see Microbiome Prescription

DataPunk.net Data

INHIBITED BY

• Flaxseed [parent]

ENHANCED BY

• Walnuts [parent]
• Saccharomyces boulardii [parent]

PubMed Data

There are 3+ studies on PubMed

Disease

Diet

Prebiotic

Probiotic

Antibiotic

Bottom Line

Avoid

• Walnuts
• Saccharomyces boulardii 

Take

• Flaxseed 

For updated information see Microbiome Prescription

DataPunk.net Data

Nothing

PubMed Data

There are 180+ studies on PubMed.

Disease

• “Subjects with ultrasound evidence of enthesitis were enriched in Campylobacter, while subjects with uveitis and radiographic sacroiliitis were respectively enriched in Erwinia and unclassified Ruminococcaceae, and both enriched in Dialister. ” [2017]
• “observed the declined abundance of Prevotella_9 and Dialister,in  Hypothyroid Hashimoto’s thyroiditis ” [2017]
• “In IBS, Dialister spp. and then Faecalibacterium prausnitzii were the most representative species. ” [2018]
• “The genera Haemophilus (log₂ fold change -2.15, P=.003), Dialister (log₂ fold change -2.22, P=.009), Dorea (log₂ fold change -1.65, P=.02), and Clostridium (log₂ fold change -1.47, P=.002) were underrepresented among subjects with food sensitization. ” [2017]
• Brief Report: Dialister as a Microbial Marker of Disease Activity in Spondyloarthritis [2017].
  • “abundance of the genus Dialister was found to be positively correlated with the Ankylosing Spondylitis Disease Activity Score “
• “At the genus level, we observed a decrease in the relative abundance of Alistipes, Bilophila, Dialister, Parabacteroides, and Veillonella in the Autism spectrum disorders  cohort, while Collinsella, Corynebacterium, Dorea, and Lactobacillus were significantly increased.” [2017]
• ” Genera Rhodococcus, Eggerthella, Klebsiella, Prevotella, Eubacterium, Flavonifractor and Incertae sedis were significantly enriched, while genera Dialister and Pseudobutyrivibrio were significantly depleted in Systemic lupus erythematosus  patients.” [2016]
• “At the genus level, the composition of Blautia was increased in T1DM group than control group whereas the composition of Haemophilus, Lachnospira, Dialister, and Acidaminococcus was decreased” [2016]

Diet

• “48 OTUs increased by 12.8-fold, including Lactobacillaceae (8 of 9 belonging to Lactobacillus), Ruminococcaceae (6 of 11 belonging to Faecalibacterium), and Veillonellaceae (8 of 15 belonging to Dialister) from taking  α-glucosidase inhibitor acarbose “
• ” At the genus level, Dialister, Dorea, Pseudobutyrivibrio, and Veillonella, belonging to the Firmicutes phylum, had statistically significant reduction with oral supplementation with L-glutamine” [2015]
• “The inclusion of whole-grain barley enriched the genera Roseburia, Bifidobacterium and Dialister, and the species Eubacterium rectale, Roseburia faecis and Roseburia intestinalis. ” [2013]

Prebiotics

Probiotics

• “Reutericyclin producing L. reuteri increased the abundance of Dialister spp. and Mitsuokella spp. (P < 0.05) ” [2015]
• “[Lactobacillus acidophilus NCFM (10(9) CFU) and cellobiose (5 g)] ..The synbiotic increased levels of Lactobacillus spp. and relative abundances of the genera Bifidobacterium, Collinsella, and Eubacterium while the genus Dialister was decreased (P < 0.05). [2014]
• “In addition, the Enterococcus faecium NCIMB 11181  probiotic-fed group featured elevated levels of Lactobacillus, Enterococcus, Oscillibacter, Succinivibro, and Clostridium genera and decreased levels of Escherichia and Dialister genera, compared with the control group. ” [2015]

Antibiotics

• ” The end of ciprofloxacin treatment correlated with a reduced proportion of Bifidobacterium (Actinobacteria), Alistipes (Bacteroidetes) and four genera from the phylum Firmicutes (Faecalibacterium, Oscillospira, Ruminococcus and Dialister) and an increased relative abundance of Bacteroides (Bacteroidetes) and the Firmicutes genera Blautia, Eubacterium and Roseburia. ” [2015]

Bottom Line

Avoid

• Lactobacillus Reuteri
• Barley

Take

• L-glutamine
• Lactobacillus acidophilus
• Cellobiose

For updated information see Microbiome Prescription

DataPunk.Net Data

Nothing

PubMed Data

There are 16+  studies on PubMed

Disease

• “Genera Rhodococcus, Eggerthella, Klebsiella, Prevotella, Eubacterium, Flavonifractor and Incertae sedis were significantly enriched, while genera Dialister and Pseudobutyrivibrio were significantly depleted in Systemic lupus erythematosus  patients. ” [2016]

Diet

• “In addition, Flavonifractor,
  Intestinimonas were found lower in inulin (IN) and inulin+wheat bran (WB) groups compared to control group.” [2017]

Prebiotics

Probiotics

• “After one month of probiotic Lactobacillus kefiri LKF01  oral intake we observed a reduction of Bilophila, Butyricicomonas, Flavonifractor, Oscillibacter and Prevotella. ” [2017]

Antibiotics

• “H. pylori Eradication therapy led to a decrease in the representation of the genera Coprococcus, Bifidobacterium, Collinsella, and an increase in the number of Clostridium, Bacteroides, Coprobacillus and Flavonifractor. ” [2015]

Bottom Line

Avoid

Take

• Lactobacillus kefiri LKF01
• Inulin

For updated information see Microbiome Prescription

DataPunk.Net Data

Nothing

PubMed Data

There are 10+ studies on PubMed

Disease

• “This was accompanied by a reduced relative abundance of the genera Collinsella (P = 0.02), Enterorhabdus (P = 0.02), and Gordonibacter (P = 0.02) in smokers with Crohn’s Disease.” [2016]
• “the abundance of the genera Enterorhabdus, Howardella, and Slackia was higher in prediabetic . ” [2015]
• “, genera significantly less abundant in collagen-induced arthritis-susceptible mice prior to arthritis onset than in CIA-resistant mice included Enterorhabdus, Alistipes, Desulfovibrio, and others (Fig. 2B and Supplementary Table 1). After arthritis onset, Enterorhabdus dramatically increased in abundance as arthritis progressed in CIA-susceptible mice. ” [2016]

Diet

• “Lauric acid… populations of Prevotella, Bacteroides, and Enterorhabdus were decreased (P = 0.04 to P < 0.001) by more than 2-fold ” [2012]
• ” there was enrichment of different taxonomic groups (Burkholderiales, Sutterellacae, Parasutterella, Betaproteobacteria, Enterorhabdus and other OTUs) in mice treated with Glucevia[ Fraxinus angustifolia Vahl samara extract] in comparison to untreated mice” [2017]
• “At the genus level, Alistipes, Christensenellaceae_uncultured, Enterorhabdus, Lactobacillus, Parabacteroides, Parasutterella, Rikenella, Ruminococcaceae_incertae_sedis, Ruminococcaceae_unclassified, and Ruminococcaceae_uncultured were reduced in the high fat group compared with the control” [2017]
• Sodium Butyrate increases [2017]

Prebiotics

•  “xylooligosaccharide significantly decreased or reversed the increase in abundance of Howardella, Enterorhabdus, and Slackia observed in healthy or Pre-DM subjects.” [2015]

Probiotics

Antibiotics

• “vancomycin-imipenem groups indicated significant depletion of large numbers of taxa, including in members of the Bacteroidetes phylum (Odoribacter, Alistipes, Bacteroides, Parabacteroides, RC9, S24-7), Firmicutes phylum (Roseburia, Candidatus arthromitus, Clostridium, and Turicibacter), and Enterorhabdus, as well as members of the Lachnospiraceae, Ruminococcaceae, Prevotellaceae” [2017]

Bottom Line

Avoid

• Sodium Butyrate

Take

• Xylooligosaccharide
• Smoking (!?!)
• Coconut Oil, Monolaurin (Lauric Acid)

This bacteria converts lysine stoichiometrically into butyrate[2016].[2015] .

For updated information see Microbiome Prescription

DataPunk.Net Data

Nothing

PubMed Data

There are 7+ studies on PubMed.

Disease

• ” the levels of Haemophilus, Lachnospira, Intestinimonas, Dialister, Micrococcales, Pasteurellaceae, and Caulobacterales were remarkable lower than those in control group in  children with newly diagnosed type 1 diabetes mellitus” [2016]
• “With Sjögren syndrome there were significant decreases in Blautia, Alistipes, Lactobacillus, Allobaculum, Bacteroides, Desulfovibrio, Intestinimonas, and Clostridium, while there were significant increases in Enterobacter, Parasutterella, Escherichia/Shigella, Pseudomonas, Staphylococcus” [2016]
• ” The expression of TNF-α was negatively correlated with the abundance of Intestinimonas-, Subdoligranulum-, and Ruminococcaceae-related OTUs.” [2016]

Diet

• “One-week High Fat Diet feeding led to elevation of Intestinimonas, Christensenella, Desulfovibrio, Candidatus_Saccharimonas and some unclassified genera but abundance declines for Lactobacillus, Akkermansia”

Prebiotics

• “In addition, Flavonifractor, Intestinimonas were found lower in inulin (IN) and wheat bran + Inulin(WB) groups compared to CON group. ” [2017]

Probiotics

Antibiotics

Bottom Line

Avoid

• Lysine supplements and foods
• High Fat Diet

Take

• Inulin