Reducing Dorea genus

The  bacteria is dorea formicigenerans reported to be low in most CFS patients by Ian Lapkin et al 2017 paper

For updated information see Microbiome Prescription


Parent means this bacteria parent, Lachnospiraceae   is influenced (this and other siblings may be my inference).




PubMed Data

There are 70+ studies on PubMed (300 by the author Dórea )

  • Disease:
    • ” This resulted from an approximately 1.5-fold increase in numbers of Dorea, ” [2011]
    • “We observed an increased abundance of Psuedomonas, Mycoplana, Haemophilus, Blautia, and Doreagenera in Multiple sclerosis  patients, [2016]
    • “patients in remission from Crohn’s disease had increased proportions of Dorea longicatena” [2016]
    • ” Dorea, … were significantly increased in Autism spectrum disorders” [2017] [2016]
    • “Parkinson’s disease  reduced content of Dorea,” [2017]
    • ” Dorea …were underrepresented among subjects with food sensitization.” [2017]
    • “Dorea spp. were found in an increased in abundance in both pediatric and adult irritable bowel syndrome patients (Rajilić-Stojanović et al., 2011; Saulnier et al., 2011), which probably could explain the symptom of bloating, experienced by the majority of these patients.”
  •  Diet:
    • ” At the genus level, consumption of 3 g/d HMW β-glucan increased Bacteroides (P < 0.003), tended to increase Prevotella (P < 0.1) but decreased Dorea (P < 0.1), ” [2016]
    • “The barley group had higher abundances of Akkermansia, Ruminococcus, Blautia, and Bilophila. Turicibacter and Roseburia were more abundant in the malt group, and [reduced] Parabacteroides, Dorea” [2015]
      • “High Molecular Weight Barley β-Glucan .. decreased Dorea” [2016]
      • “whole-grain barley and barley malt, decreases” [2015]
    • “23 healthy subjects were randomised into two study groups consuming a bowel preparation (Moviprep)…increased the levels of Proteobacteria, Fusobacteria and bacteria related to Dorea formicigenerans.” [2015]
    • ” At the genus level, Dialister, Dorea, Pseudobutyrivibrio, and Veillonella, belonging to the Firmicutes phylum, had statistically significant reduction with l-glutamine” [2015]
    • Stressor-induced increases in circulating IL-6 and MCP-1 were significantly correlated with stressor-induced changes in 3 members of the microbiota, Dorea spp., Coprococcus spp., and Pseudobutyrivibrio spp.” [2011]
    • “The relative abundance of sequences from several genera belonging to the Lachnospiraceae (eg, RuminococcusRoseburiaBlautia, and Dorea) was lower in high … vitamin D quartiles. “
    • ” the animal-based diet caused a significant increase in the relative abundance of Bilophila, Odoribacter, Dorea and Ruminococcus (belonging to Lachnospiraceae) and a significant decrease in the level of Bifidobacterium after five days of intake. ” [2016]
    • “Among others, bacteria of the order Lactobacillales, the family Enterococcaceae and genera Enterococcus and Doreashowed a trend towards increased abundance in Tc+ (Helminth infections) ” [2016]
    • ” iron sulfate (Oral) treatment was associated with decreased abundances of operational taxonomic units assigned to the species Faecalibacterium prausnitziiRuminococcus bromiiDorea sp. and Collinsella aerofaciens. “
    • “Alcohol …  significant reductions in genra Clostridium IV and XIVb (p<0.001), Dorea (p<0.01), [2017]
  • Prebiotics:
    • “galactooligosaccharides (GOS) ..showed a decrease in Dorea “[2009]
    • “prebiotic (fructo-oligosaccharides (FOS) and inulin mixture)..revealed a lower abundance of Dorea” [2017]
  • Probiotics:
    • Lactobacillus rhamnosus hsryfm 1301,…was changed significantly after probiotic intervention for 28 d (P < 0.05). A positive correlation was observed between Ruminococcus spp. and serum triglycerides, Dorea spp. ” [2014] [2013]
    • Bifidobacterium longum increases two strains that increase Dorea. {Pdf]
  • Antibiotics:
    • “decreased after treatment only in the antibiotic (amoxicillin, tetracycline and metronidazole for 2 weeks)  group. Eubacterium rectale, Dorea formicigenerans,” [2005]

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