Reducing Dorea genus

The  bacteria is dorea formicigenerans reported to be low in most CFS patients by Ian Lapkin et al 2017 paper

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Parent means this bacteria parent, Lachnospiraceae   is influenced (this and other siblings may be my inference).

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PubMed Data

There are 70+ studies on PubMed (300 by the author Dórea )

  • Disease:
    • ” This resulted from an approximately 1.5-fold increase in numbers of Dorea, ” [2011]
    • “We observed an increased abundance of Psuedomonas, Mycoplana, Haemophilus, Blautia, and Doreagenera in Multiple sclerosis  patients, [2016]
    • “patients in remission from Crohn’s disease had increased proportions of Dorea longicatena” [2016]
    • ” Dorea, … were significantly increased in Autism spectrum disorders” [2017] [2016]
    • “Parkinson’s disease  reduced content of Dorea,” [2017]
    • ” Dorea …were underrepresented among subjects with food sensitization.” [2017]
    • “Dorea spp. were found in an increased in abundance in both pediatric and adult irritable bowel syndrome patients (Rajilić-Stojanović et al., 2011; Saulnier et al., 2011), which probably could explain the symptom of bloating, experienced by the majority of these patients.”
  •  Diet:
    • ” At the genus level, consumption of 3 g/d HMW β-glucan increased Bacteroides (P < 0.003), tended to increase Prevotella (P < 0.1) but decreased Dorea (P < 0.1), ” [2016]
    • “The barley group had higher abundances of Akkermansia, Ruminococcus, Blautia, and Bilophila. Turicibacter and Roseburia were more abundant in the malt group, and [reduced] Parabacteroides, Dorea” [2015]
      • “High Molecular Weight Barley β-Glucan .. decreased Dorea” [2016]
      • “whole-grain barley and barley malt, decreases” [2015]
    • “23 healthy subjects were randomised into two study groups consuming a bowel preparation (Moviprep)…increased the levels of Proteobacteria, Fusobacteria and bacteria related to Dorea formicigenerans.” [2015]
    • ” At the genus level, Dialister, Dorea, Pseudobutyrivibrio, and Veillonella, belonging to the Firmicutes phylum, had statistically significant reduction with l-glutamine” [2015]
    • Stressor-induced increases in circulating IL-6 and MCP-1 were significantly correlated with stressor-induced changes in 3 members of the microbiota, Dorea spp., Coprococcus spp., and Pseudobutyrivibrio spp.” [2011]
    • “The relative abundance of sequences from several genera belonging to the Lachnospiraceae (eg, RuminococcusRoseburiaBlautia, and Dorea) was lower in high … vitamin D quartiles. “
    • ” the animal-based diet caused a significant increase in the relative abundance of Bilophila, Odoribacter, Dorea and Ruminococcus (belonging to Lachnospiraceae) and a significant decrease in the level of Bifidobacterium after five days of intake. ” [2016]
    • “Among others, bacteria of the order Lactobacillales, the family Enterococcaceae and genera Enterococcus and Doreashowed a trend towards increased abundance in Tc+ (Helminth infections) ” [2016]
    • ” iron sulfate (Oral) treatment was associated with decreased abundances of operational taxonomic units assigned to the species Faecalibacterium prausnitziiRuminococcus bromiiDorea sp. and Collinsella aerofaciens. “
    • “Alcohol …  significant reductions in genra Clostridium IV and XIVb (p<0.001), Dorea (p<0.01), [2017]
  • Prebiotics:
    • “galactooligosaccharides (GOS) ..showed a decrease in Dorea “[2009]
    • “prebiotic (fructo-oligosaccharides (FOS) and inulin mixture)..revealed a lower abundance of Dorea” [2017]
  • Probiotics:
    • Lactobacillus rhamnosus hsryfm 1301,…was changed significantly after probiotic intervention for 28 d (P < 0.05). A positive correlation was observed between Ruminococcus spp. and serum triglycerides, Dorea spp. ” [2014] [2013]
    • Bifidobacterium longum increases two strains that increase Dorea. {Pdf]
      relationships
  • Antibiotics:
    • “decreased after treatment only in the antibiotic (amoxicillin, tetracycline and metronidazole for 2 weeks)  group. Eubacterium rectale, Dorea formicigenerans,” [2005]

Bottom Line

Avoid

Take