Reducing Blautia genus

High blautia has been seen frequently with CFS (see this earlier post and this one with samples)

DataPunk.Net Data

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PubMed Data

Disease:

  • Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder[20176]
    • “A significant increase in several mucosa-associated Clostridiales was observed in ASD-FGID, whereas marked decreases in Dorea and Blautia, as well as Sutterella, were evident. “
  • “At the taxonomic level of genus, putative, “anti-inflammatory” butyrate-producing bacteria from the genera Blautia, Coprococcus, and Roseburia were significantly more abundant in feces of controls than Parkinson’s Disease patients” [2015]  i.e. low levels => PD
  • “We observed an increased abundance of Psuedomonas, Mycoplana, Haemophilus, Blautia, and Doreagenera in Multiple sclerosis  patients, [2016]
  • Hints that it may be high with MCS (see this post)
  • “unlike those of healthy infants, feces of Autism Spectrum Disorder infants had significantly higher and lower abundance of genera Faecalibacterium and Blautia, respectively.” [2016]
  • Diabetes: ” Microbiota in the samples was predominantly represented by Firmicutes, in a less degree by Bacteroidetes. Blautia was a dominant genus in all samples. The representation of Blautia, Serratia was lower in preD than in T2D patients, and even lower in those with normal glucose tolerance.”[2016]
  • “Fecal microbial communities were more similar among UC patients than their healthy partners (P = 0.024). ulcerative colitis  individuals had a lower relative abundance of bacteria belonging to the Firmicutes, especially BlautiaClostridiumCoprococcus and Roseburia (P < 0.05). ” [2017]
  • “. At the species level, butyrate-producing bacterial species, such as Blautia faecis, Roseburia inulinivorans, Ruminococcus torques, Clostridium lavalense, Bacteroides uniformis and Faecalibacterium prausnitzii were significantly reduced in Crohn’s disease  patients ” [2016]
  • “The intestinal microbiota of elderly manifested a reduction in the diversity, characterized by a large interindividual variability, with lower numbers of FirmicutesBifidobacteriaClostridium clusterXIV, Faecalibacterium PrausnitziiBlautia coccoides-Eubacterium rectal ” [2015]

Diet:

  • “some bile acids have been shown to exhibit antimicrobial activity….bactericidal activities to Blautia coccoides” [2017]
  • sodium butyrate …. elevated the abundances of the beneficial bacteria ChristensenellaceaeBlautia and Lactobacillus.”[2017]
  • safflower oil…increased abundance of Blautia,[2016]
  • Japanese traditional dietary fungus koji Aspergillus oryzae functions as a prebiotic for Blautia coccoides through glycosylceramide: Japanese dietary fungus koji is a new prebiotic [2016].
  • Metformin and berberine.…were markedly increased” [2015] [2016]
  • Resistant starch (RS) …  Roseburia, Blautia, and Lachnospiracea incertae sedis were decreased.” [2015] [2016][2014]
  • High grain diet …altered the colonic mucosal bacterial communities, with an increase in the abundance of genus Blautia and a decrease in the abundance of genera Bacillus, Enterococcus, and Lactococcus.”
  • “antimicrobial effect observed for the grape seed polyphenols, particularly against Bacteroides, Prevotella and Blautia coccoides-Eubacterium rectale.” [2015]
    • “Subjects with regular consumption of red wine (mean = 100 ml/day) had lower serum concentrations of MDA and lower fecal levels of… blautia”[2015]
  • “positive associations between flavone intake and Blautia,” [2015]
  • “A negative association was found between the intake of pectins and flavanones from oranges and the levels of Blautia coccoides” [2014]
  • Rosemary Extract …increased the Blautia coccoides and Bacteroides/Prevotella groups and reduced the Lactobacillus/Leuconostoc/Pediococccus group in both types of animals.” [2014]
  • ” All treatments [a daily dose of 60 g of whole-grain barley (WGB), brown rice (BR), or an equal mixture of the two (BR+WGB)] increased microbial diversity, the Firmicutes/Bacteroidetes ratio, and the abundance of the genus Blautia in fecal samples.”
  • “At the end of the 2-week omega-3 rich diet, we identified a striking reduction in Faecalibacterium, and a remarkable increase in Blautia” [2016]
  • “The relative abundance of sequences from several genera belonging to the Lachnospiraceae (eg, RuminococcusRoseburiaBlautia, and Dorea) was lower in high … vitamin D quartiles. “ [2015]

Probiotics:

  • “Bifidobacterium longum BB536 and  Lactobacillus rhamnosus .., a higher abundance of Blautia productaBlautia wexlerae ” [2017]
  • ” least 24 billion viable Lactobacillus paracasei DG …the Clostridiales genus Blautia (P = 0.036) was decreased;”
  • ” Blautia, Roseburia and Coprococcus were significantly enriched following treatment with hydrolyzed casein formula supplemented with Lactobacillus rhamnosus GG” [2016]
  • Blautia and Staphylococcus) significantly increased after Lactobacillus plantarum P-8 consumption,” [2015]
  • Lactobacillus salivarius Ls-33…Blautia coccoides_Eubacteria rectale group and Roseburia intestinalis, were significantly increased” [2013]
  • “Bacillus subtilis…the relative abundance of Alistipes, Odoribacter, Ruminococcus, Blautia and Desulfovibrio were higher” [2016]

Antibiotics:

  • “Ten OTUs indicating fluoroquinolone treatment were associated with Blautia, Subdoligranulum, Adlercreutzia, Clostridium and Ruminococcus.” [2014]

Bottom Line

Avoid

Take

  • Oranges (pectin/flavanones)
  • Grape seed polyphenols,/ Wine
  • 24 billion viable Lactobacillus paracasei  daily
  • Bile acid
  • Flaxseed
  • Vitamin D3