Hypertension – What we know

As a result of my last post, several reader pinged my about hypertension, in some cases associated with POTS (a common morbidity with ME/CFS). This is just a quick recap of recent research.

The age-standardized prevalence of hypertension at baseline was 74.3% for men and 70.2% for women.

Prevalence and Incidence of Hypertension in the General Adult Population [2015]
Prevalence and Incidence of Hypertension in the General Adult Population [2015]
Follow up 1 is 4 years later, 2 is 2 more years
  • ” Obesity and weight gain also contributed to progression; a 5% weight gain on follow-up was associated with 20-30% increased odds of hypertension. ” [2001]
  • “Dose-response analyses showed that all of the carotenoids[ β-cryptoxanthin, lycopene, lutein with zeaxanthin and total carotenoids ] were inversely associated with hypertension in a linear manner. Total carotenoids showed significant effect of lower risk of hypertension at 100 μg/kg per day. “[2019]
  • ” It appears that the use of nutritional supplements and medical foods containing L-methylfolate and vitamin D may be effective in facilitating the improvement of diabetic and hypertensive retinopathy.”[2019] “
  • ” In conclusion, higher dietary calcium intake, independent of adiposity and intake of other blood pressure-related minerals, is slightly associated with a lower risk of developing hypertension. ” [2019]
  • Zinc deficiency is an independent risk factor for prehypertension in healthy subjects. [2019]
  • ” When studies were categorized based on participants’ mean age, ginger dosage and duration of intervention, systolic BP and diastolic BP were significantly decreased only in the subset of studies with mean age ≤ 50 years, follow-up duration of ≤8 weeks and ginger doses ≥3 g/d.  ” [2019]
  • Cross-sectional NHANES data do not support the hypothesis of a positive association between choline intake and BP. [2019]

A nice summary article

Nutrients and Nutraceuticals for the Management of High Normal Blood Pressure: An Evidence-Based Consensus Document. [2019]
Nutrients and Nutraceuticals for the Management of High Normal Blood Pressure: An Evidence-Based Consensus Document. [2019]
Nutrients and Nutraceuticals for the Management of High Normal Blood Pressure: An Evidence-Based Consensus Document. [2019]

Other antihypertensives

That is, BP lowering substances, not cited above:

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