Hemex was subsequently purchased and David Berg’s ISAC panel was subsequently dropped. His studies found that over 70% of CFS/ME patients have hypercoagulation which was often a major factor for symptoms and for successful treatment.
A reader surprised me this week because a German lab had worked with David Berg and implemented the ISAC panel — and continue to offer it.
Antibiotic therapy and no recognizable improvement in symptoms?
In more than 60% of all bacterial infectious diseases, the pathogens form biofilms, which protect them from attack by the immune system. The hematologist D. Berg has developed the “ISAC” protocol to recognize a biofilm. (ISAC: Immune System Activation of Coagulation). When a biofilm is detected, he recommends the use of lumbrokinase for removal. The new formation of a biofilm during the therapy is prevented eg. by low molecular weight heparin. The Dedimed Europarc Laboratory carries out the biofilm testing, which we recommend before any lengthy antibiosis.
I talked to Dr. Waldherr for 45 minutes he is unbelievable good informed about almost everything and he said to me, that he and his colleagues reached up to Dr. Berg to finde out how to perform the tests. The actual test is done in Berlin from Dr. Sucker and the treatment is then given low molecule Heparin etc. he also knows all the enzymes used like Nattokinase, Lumbrokinase etc. he also speaks English which is also a good thing if people don’t speak german.
On Feb 15th I was running a high temperature, definitely coming down with something and the next day I had a seizure (my first one ever). I was sent to hospital and stayed there for several days. This post record some interesting observations both as a ME/CFS person and a person with an unknown virus (not COVID-19) that echo some aspects reported for COVID-19.
I happened to be wearing a watch (Cheap $18 watch from China) that records my pulse and blood pressure every hour. This is what was recorded. Impressive changes
The symptoms presented like sepsis, so I was placed on multiple high dosage antibiotics. Testing found nothing (Flu, bacteria, and even a spinal tap to check for meningitis). Many CRT and MRI scans. Nothing was found so the most likely cause was a viral infection of unknown type.
The fever lasted for about 3 days. I was given beta blockers, heparin etc.
It was measured by the ambulance crew and was at the high end of the normal range. For the next three days it was quite high outside of the normal range. On day 4 it returned to the middle of the normal range.
This is significant for COVID-19, because people with high blood sugar (diabetes) have a higher fatality rate. I suspect that the same increase of blood pressure pushes things still higher to the lethal range in some.
If your examine my post on another blog on symptoms, you will see that high values of c reactive protein are associated with higher death rates for Covid-19 [PubMed]
Blood Pressure and Pulse
These stayed high and were still abnormally high at discharge. I started on supplements proven in studies to lower blood pressure, and they helped quickly but BP stayed erratic (jumping from normal to high for 2 hrs and then back), just less so over time.
A reader referred me to this study of MERS-CoV, another Coronavirus. The item that helped was resveratrol, which also lowers blood pressure (may be the mechanism it works thru).
The moment that I got home, I did a microbiome test (Thryve) with a primary focus on correcting changes from the antibiotics. For the abnormal high blood pressure, I hit it with literally everything that was documented (see here for the list). Blood pressure and pulse initially went back to normal and then started jumping around with no apparent explanation at the time.
Oops on Supplements
I received my Thryve microbiome results and was not surprise to see the chart shown below. It indicated that the jump of blood pressure was a result of microbiome changes induced by the virus.
I then identified which shifts were key:
The interesting thing was that comparing the recommendations for this mixture and the studies, we had good overlap — but a few appear on the avoid list. I removed those from my supplements, and things improved more.
It illustrates that results from the general population may not apply to an individual. I had a subset of the high BP bacteria and being specific to those bacteria is preferred.
Hypercoagulation vs Pulse and Blood Pressure
One of the things that I noticed was that my 02 saturation was not the normal 99%. A rock steady 99%.
When my pulse and BP went to normal for a few hours, O2 dropped to 94%
When my pulse and BP went high, my O2 returned to 99%
Conversations with Dave Berg, Hemex Labs, came back. Infections often trigger coagulation (blood thickening). The light went on! The increase of both pulse and blood pressure may be a response to the low O2 level and an attempt to restore O2 levels.
As a side note, the hypercoagulation is suspected by some to play a role in postural orthostatic tachycardia syndrome (POTS). The thick blood results in delay of blood pressure in the body resulting in mis-signalling. The rapid increase in heartbeat seen with POTS is an attempt to compensate.
Heart rate and blood pressure work together to keep the blood flowing at a healthy pace, no matter what position the body is in. People with POTS cannot coordinate the balancing act of blood vessel squeeze and heart rate response. This means the blood pressure cannot be kept steady and stable….. Patients may develop POTS after a viral illness,
I know from ME/CFS days that I have an inherited coagulation defect [Prothrombin G20210A or factor II mutation]. I am one of the lucky ones because there are known substances that will compensate for my particular defect: Piracetam, with tumeric being a secondary choice. I proceeded with 1200 mg of Piracetam with each meal. O2 levels went up, pulse and BP went down more. See below
I have a follow up in 2 weeks with my MD and hope to get some heparin to take sublingually (under tongue, not by needle) to further clear the hypercoagulation.
It was interesting to see that this unknown virus caused changes in blood sugar and blood pressure. For COVID-19, there are higher death rates (about 9-10%) for people with diabetes (high glucose) and hypertension (high blood pressure) – I suspect that COVID-19 pushes these to potentially fatal levels.
Takeaways: reducing BP and blood sugar proactively and aggressively may be a good strategy. High BP may be connected with hypercoagulation (which may be sub-clinical, i.e. not severe enough for physicians to take action).
In short, ME/CFS patients are older. Corvid-19 kills older people more often (over 20% in some age ranges). This computes the risk over all ages with ME/CFS. ME/CFS is not causing this high rate, patient ages are.
For reference, Flu Death Rate from CDC for 2018-2019: (=34,157/35,520,883) or 0.0962%. So the risk of death is 46.8x more
This is the protocol that was responsible for one of my remissions. My current belief is that what she termed “occult rickettsia infection” is “post-infection stable microbiome dysfunction”. Regardless, the treatment works in a high ( > 75%) of ME/CFS patients. The treatment was evolved prior to the microbiome entering research, using real patients over many years at the Pasteur Institute for Tropical Medicine.
Objective: To demonstrate the probable role of intracellular bacteria like Rickettsiae and Chlamydiae in the development of certain chronic psychopathological conditions and according to the efficiency of antibiotic regimes (minocyclines and/or macrolides). The letter aim is based on the fact that all the patients that I have seen since 1981 had a sera reaction positive for Rickettsiae and/or Chlamydiae using the micro-agglutination on blade technique of P. Giroud and M.L. Giroud (MAG) by Prof. J.B. Jadin of Antwerp, Belgium with special antigens cultured on guinea pig lungs and chicken embryos. Methods: This is an open study which began in 1981 in a private medical practice, not versus placebo; but with random choice. Treatment was for a minimum of six months (minocyclines and/or macrolides together with vasodilatory medication; chloroquine; warm baths). Group one: 98 CFS cases; women: 78, men: 20; for 67 cases, the ancientness of symptoms is more than 2 years. Group two: 59 psycho-somatic cases; 5 schizophrenia; 3 borderline; 10 children with aggressivity, excitement; 1 autistic child; 1 delirium with relapses. Results: Group one: 79.5% good and very good results; 4.1% fairly good; 16.4% failed. Group two: 82.3% good and very good results; 2.5% fairly good; 15.2% failed. Conclusion: This diagnostic and therapeutic study began in 1981. All of the Dr. Bottero’s therapeutic results are confirmed since 1991 by Dr. Cecile Jadin of Randburg (South Africa) for more than 3000 CFS and other psychopathological states (300): Sydney 98 CFS Conference, Australia. We have shown that Rickettsiae and Chlamydiae are probably causative factors in many “psychopathologies.”
David M. ask me about comparing results from different providers of FastQ to Taxon. I had coded it out and was unhappy with what I saw and did not post about it . I had missed a bug and while the link was there – it would error out. That bug is now fixed, and you may use it..,